2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. AChE-IN-56

AChe-IN-56 is an orally active inhibitor for acetylcholinesterase enzyme (AChE) with neuroprotective efficacy.

For research use only. We do not sell to patients.

AChE-IN-56 Chemical Structure

AChE-IN-56 Chemical Structure

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AChE-IN-56 Related Antibodies

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Description

AChe-IN-56 is an orally active inhibitor for acetylcholinesterase enzyme (AChE) with neuroprotective efficacy[1].

IC50 & Target

AChE

 

In Vivo

AChe-IN-56 (2 mg/kg, p.o., 5 days) exhibits an inhibitory efficacy in scopolamine-induced memory impairment and learning disability in Swiss albino mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: scopolamine-induced memory and learning disability in swiss albino mice [1]
Dosage: 2 mg/kg
Administration: p.o., for 5 days
Result: Reduced escape latency, restored the levels of AChE, lipids peroxidation, nitrit and oxidative stress and inhibited the production of ROS and RNS.
Molecular Weight

509.02

Formula

C23H29ClN4O5S
SMILES

O=S(C1=CC=C(Cl)C=N1)(NC2CCN(C3C(N(CC4=CC=C(OC)C(OC)=C4)CC3)=O)CC2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AChE-IN-56 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE-IN-56Cholinesterase (ChE)Alzheimer’s diseaseescape latencyswiss albino miceInhibitorinhibitorinhibit

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HY-161243
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