2. GPCR/G Protein Metabolic Enzyme/Protease
  3. Prostaglandin Receptor Lipoxygenase
  4. Canniprene

Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa, is a potent inhibitor of 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; IC50=10 μM). Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins.

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Canniprene Chemical Structure

Canniprene Chemical Structure

CAS No. : 70677-47-3

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Canniprene Related Antibodies

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Description

Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa, is a potent inhibitor of 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; IC50=10 μM). Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins[1].

IC50 & Target[1]

5-LO

0.4 μM (IC50)

PGE2

10 μM (IC50)

Molecular Weight

342.43

Formula

C21H26O4
CAS No.
SMILES

OC1=C(OC)C=CC(CCC2=CC(OC)=CC(O)=C2)=C1C/C=C(C)\C
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Canniprene Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Canniprene70677-47-3Prostaglandin ReceptorLipoxygenaseLOXCannabis sativainflammatory eicosanoidsprostaglandinspotentcyclooxygenase/microsomalInhibitorinhibitorinhibit

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