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  3. Fluorescent Dye
  4. Coumarin 7

Coumarin 7 is a coumarin laser dye in plants in the form of glycosides.

For research use only. We do not sell to patients.

Coumarin 7 Chemical Structure

Coumarin 7 Chemical Structure

CAS No. : 27425-55-4

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100 mg USD 30 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Coumarin 7 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Coumarin 7 is a coumarin laser dye in plants in the form of glycosides[1][2].

Cellular Effect
Cell Line Type Value Description References
H9 CC50
> 50 μM
Compound: 53
Cytotoxicity against human H9 cells by MTS assay
Cytotoxicity against human H9 cells by MTS assay
[PMID: 25847768]
H9 IC50
0.24 μM
Compound: 53
Antiviral activity against X4 tropic HIV-1 clone pNL4-3 infected in H9 cells assessed as reduction in p24 antigen after 4 days by ELISA
Antiviral activity against X4 tropic HIV-1 clone pNL4-3 infected in H9 cells assessed as reduction in p24 antigen after 4 days by ELISA
[PMID: 25847768]
In Vitro

Coumarin 7 has the maximum CL intensity (Imax=0.39×10-9 photon/sml), total amount of light (S=0.07×10-10 photon/mL) and the yield of CL (φCL=0.12×108 Einstein/mol)[2]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Coumarin 7 Related Antibodies
Molecular Weight

333.38

Formula

C20H19N3O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

Emission (Em)

438
Excitation (Ex)

344
SMILES

O=C1C(C2=NC3=CC=CC=C3N2)=CC4=CC=C(N(CC)CC)C=C4O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (37.49 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9996 mL 14.9979 mL 29.9958 mL
5 mM 0.5999 mL 2.9996 mL 5.9992 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.80%

SDS (393 KB)

COA (249 KB) HNMR (138 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9996 mL 14.9979 mL 29.9958 mL 74.9895 mL
5 mM 0.5999 mL 2.9996 mL 5.9992 mL 14.9979 mL
10 mM 0.3000 mL 1.4998 mL 2.9996 mL 7.4990 mL
15 mM 0.2000 mL 0.9999 mL 1.9997 mL 4.9993 mL
20 mM 0.1500 mL 0.7499 mL 1.4998 mL 3.7495 mL
25 mM 0.1200 mL 0.5999 mL 1.1998 mL 2.9996 mL
30 mM 0.1000 mL 0.4999 mL 0.9999 mL 2.4997 mL
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Coumarin 7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Coumarin 727425-55-4Coumarin7Coumarin-7Fluorescent DyeInhibitorinhibitorinhibit

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