2. Membrane Transporter/Ion Channel PI3K/Akt/mTOR NF-κB
  3. Na+/K+ ATPase Akt NF-κB
  4. Cryptanoside A

Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB.

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Cryptanoside A Chemical Structure

Cryptanoside A Chemical Structure

CAS No. : 98570-81-1

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Cryptanoside A Related Antibodies

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Akt Akt1 Akt2 Akt3

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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Description

Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB[1].

Molecular Weight

562.65

Formula

C30H42O10
CAS No.
SMILES

O[C@@]([C@@]1(C2=O)C)(CC[C@]1([H])C(CO3)=CC3=O)[C@]4([C@@](C[C@]5([H])C[C@H]6O[C@H](O[C@H]7C)C[C@@H]([C@H]7O)OC)([H])O4)[C@@]([C@@H]2O)([H])[C@]5(CC6)C
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cryptanoside A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cryptanoside A98570-81-1Na+/K+ ATPaseAktNF-κBSodium potassium pumpPKBProtein kinase BNuclear factor-κBNuclear factor-kappaBCancerglycoside epoxidecardiacNa+/K+-ATPaseInhibitorinhibitorinhibit

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