Eugenin

Name: Eugenin
Brand: MedChemExpress
SKU: HY-33351
Rating: 4.5 (1 reviews)

Cat. No.: HY-33351 Purity: 99.02%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Eugenin is a chromone isolated from Peucedanum japonicum, with potent antiplatelet aggregation activity.

For research use only. We do not sell to patients.

Eugenin Chemical Structure

CAS No. : 480-34-2

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 165	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 165	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 950	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 1550	Get quote	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Eugenin is a chromone isolated from Peucedanum japonicum, with potent antiplatelet aggregation activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	GI₅₀	14 μM Compound: 4	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 19405508]
HT-29	GI₅₀	25 μM Compound: 4	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 19405508]
MCF7	GI₅₀	10 μM Compound: 4	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 19405508]

Molecular Weight

206.19

Formula

C₁₁H₁₀O₄

CAS No.

480-34-2

Appearance

Solid

Color

White to off-white

SMILES

O=C1C=C(C)OC2=C1C(O)=CC(OC)=C2

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (242.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8499 mL	24.2495 mL	48.4990 mL
5 mM	0.9700 mL	4.8499 mL	9.6998 mL
10 mM	0.4850 mL	2.4249 mL	4.8499 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (12.12 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.02%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (249 KB) HNMR (241 KB) LCMS (269 KB)

Handling Instructions (2659 KB)

References

[1]. Chen IS, et al. Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum. Phytochemistry. 1996 Feb;41(2):525-30. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.8499 mL	24.2495 mL	48.4990 mL	121.2474 mL
	5 mM	0.9700 mL	4.8499 mL	9.6998 mL	24.2495 mL
	10 mM	0.4850 mL	2.4249 mL	4.8499 mL	12.1247 mL
	15 mM	0.3233 mL	1.6166 mL	3.2333 mL	8.0832 mL
	20 mM	0.2425 mL	1.2125 mL	2.4249 mL	6.0624 mL
	25 mM	0.1940 mL	0.9700 mL	1.9400 mL	4.8499 mL
	30 mM	0.1617 mL	0.8083 mL	1.6166 mL	4.0416 mL
	40 mM	0.1212 mL	0.6062 mL	1.2125 mL	3.0312 mL
	50 mM	0.0970 mL	0.4850 mL	0.9700 mL	2.4249 mL
	60 mM	0.0808 mL	0.4042 mL	0.8083 mL	2.0208 mL
	80 mM	0.0606 mL	0.3031 mL	0.6062 mL	1.5156 mL
	100 mM	0.0485 mL	0.2425 mL	0.4850 mL	1.2125 mL

Eugenin Related Classifications

Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eugenin480-34-2OthersInhibitorinhibitorinhibit

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Eugenin

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Complete Stock Solution Preparation Table

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