TLR8 - toll like receptor 8 Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 100684828 | Gene type: protein coding

About TLR8

Primary_assembly X: 9,347,575-9,351,742 forward strand.ROS_Cfam_1.0:CM025138.1

This gene has 1 transcript (splice variant), 199 orthologues and 19 paralogues.

TLR8 Products(2)

mRNA	Protein	Name
XM_038449411.1	XP_038305339.1	toll-like receptor 8
XM_038449410.1	XP_038305338.1	toll-like receptor 8

TLR8 Protein Structure

PRK15370

LRR_RI

PLN00113

LRR_RI

LRR_8

LRR_RI

TPKR_C2

TIR

0
200
400
600
800
1038 a.a.

Protein Preferred Names

Protein Names

toll-like receptor 8

LOW QUALITY PROTEIN: toll-like receptor 8

Related Agents

Clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13740	Resiquimod	Agonist	99.95%	Phase 2
HY-134581	Enpatoran	Inhibitor	99.77%	Phase 2
HY-13773	Motolimod	Agonist	98.12%	Phase 2
HY-109137	Selgantolimod	Agonist	98.23%	Phase 2
HY-134581A	Enpatoran hydrochloride	Inhibitor	99.33%	Phase 2
HY-13740G	Resiquimod (GMP)	Agonist	/	Phase 2
HY-109104	Telratolimod	Agonist	98.98%	Phase 1

Pre-clinical Phase

Bioactive Molecules (37)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-128799	CL097	Agonist	99.89%	Unkown
HY-117066	CL075	Agonist	99.25%	Unkown
HY-139323	TLR7/8-IN-1	Inhibitor	99.92%	Unkown
HY-103697	Gardiquimod	Agonist	99.91%	Unkown
HY-103697A	Gardiquimod diTFA	Agonist	≥99.0%	Unkown
HY-103698	TLR7/8 agonist 1	Agonist	97.33%	Unkown
HY-112050	CU-CPT-8m	Antagonist	99.98%	Unkown
HY-112667	CU-CPT-9a	Antagonist	99.36%	Unkown
HY-130797	TLR7/8 agonist 3	Agonist	99.96%	Unkown
HY-101929	CU-CPT17e	Agonist	99.00%	Unkown
HY-131945	CU-115	Antagonist	99.55%	Unkown
HY-139017	TLR7/8 agonist 4	Agonist	99.04%	Unkown
HY-112051	CU-CPT9b	Antagonist	99.03%	Unkown
HY-160229	ssRNA40 sodium	Activator	93.25%	Unkown
HY-13740S	Resiquimod-d5	Agonist	99.84%	Unkown
HY-128799A	CL097 hydrochloride	Agonist	99.51%	Unkown
HY-145960	MC-Val-Cit-PAB-Amide-TLR7 agonist 4	Agonist	99.39%	Unkown
HY-138139A	AXC-715 hydrochloride	Agonist	99.46%	Unkown
HY-153543	TLR7/8 agonist 8	Agonist	/	Unkown
HY-159102	PVP-037.2	Agonist	/	Unkown
HY-158694A	TLR7 agonist 20 hydrochloride	Agonist	99.86%	Unkown
HY-139017A	TLR7/8 agonist 4 TFA	Agonist	/	Unkown
HY-141454A	TLR8 agonist 2 hydrochloride	Agonist	/	Unkown
HY-141454	TLR8 agonist 2	Agonist	/	Unkown
HY-160228A	ORN 02 sodium	Activator	/	Unkown
HY-160228	ORN 02	Activator	/	Unkown
HY-163670	TLR7 agonist 21	Inhibitor	/	Unkown
HY-158694	TLR7 agonist 20	Agonist	/	Unkown
HY-153544	TLR7/8 agonist 9	Inhibitor	/	Unkown
HY-121496	3M-011	Agonist	/	Unkown
HY-161629	TLR8 agonist 7	Agonist	/	Unkown
HY-162845	TLR7/8 agonist 11	Agonist	/	Unkown
HY-169057	BI1543673	Inhibitor	/	Unkown
HY-161631	TLR8 agonist 9	Agonist	/	Unkown
HY-161630	TLR8 agonist 8	Agonist	/	Unkown
HY-159919	UM-3006	Agonist	/	Unkown
HY-159916	AYK004	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	TLR8	NCBI	NCBI:51311

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