2. Gene
  3. Ehd1 - EH-domain containing 1 Gene

Ehd1 - EH-domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1306960

Gene ID: 293692 | Gene type: protein coding

About Ehd1

Summary

Predicted to enable identical protein binding activity and small GTPase binding activity. Involved in cellular response to nerve growth factor stimulus; neuron projection development; and positive regulation of neuron projection development. Located in endosome membrane. Biomarker of obesity. Orthologous to human EHD1 (EH domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Ehd1 Products(1)

mRNA Protein Name
NM_001011939.2 NP_001011939.1 EH domain-containing protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11423532 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to nerve growth factor stimulus IDA
IDA: Inferred from direct assay
23572513 RGD
involved in neuron projection development IMP
IMP: Inferred from mutant phenotype
23572513 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
23572513 RGD
Cellular Component GO Annotation Evidence Reference Source
located in endosome membrane IDA
IDA: Inferred from direct assay
23572513 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20696250 RGD
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
20696250 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

EH domain-containing protein 1

Ehd1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Ehd1 Q641Z6 Pacsin2 Rattus norvegicus Q9QY17
CoIP
15371016
Intra
Ehd1 Q641Z6 Snap29 Rattus norvegicus Q9Z2P6
CoIP
15371016
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04221 EHD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ehd1 NCBI NCBI:10938