Gpr68 - G protein-coupled receptor 68 Gene

Rattus norvegicus

Gene ID: 314386 | Gene type: protein coding

About Gpr68

Primary_assembly 6: 120,135,436-120,166,089 reverse strand.mRatBN7.2:CM026979.1

This gene has 4 transcripts (splice variants), 197 orthologues, 1 paralogue and is associated with 3 phenotypes. Biased expression in Thymus (RPKM 47.3), Spleen (RPKM 36.6) and 9 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cellular response to pH. Predicted to act upstream of or within negative regulation of monocyte differentiation; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and positive regulation of osteoclast development. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 2A6. Orthologous to human GPR68 (G protein-coupled receptor 68). [provided by Alliance of Genome Resources, Apr 2022]

Gpr68 Products(1)

mRNA	Protein	Name
NM_001108049.1	NP_001101519.1	ovarian cancer G-protein coupled receptor 1

Gpr68 Protein Structure

7tmA_GPR68_OGR1

0
100
200
300
375 a.a.

Protein Preferred Names

Protein Names

ovarian cancer G-protein coupled receptor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-110279	Ogerin	Modulator	99.58%	Unkown
HY-154954	Ogremorphin	Inhibitor	99.65%	Unkown
HY-134494	MS48107		99.85%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpr68	NCBI	NCBI:8111

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