SYCN - syncollin Gene

Homo sapiens

Also known as SYL; INSSA1

Gene ID: 342898 | Gene type: protein coding

About SYCN

This gene has 1 transcript (splice variant) and 122 orthologues. Restricted expression toward pancreas (RPKM 2575.3).

Summary

Predicted to be involved in exocytosis. Predicted to be active in secretory granule membrane. [provided by Alliance of Genome Resources, Apr 2022]

SYCN Products(1)

mRNA	Protein	Name
NM_001080468.4	NP_001073937.1	syncollin precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	33961781	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SYCN Protein Structure

Syncollin

0
100
134 a.a.

Protein Preferred Names

Protein Names

syncollin

insulin synthesis associated 1

SYCN Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SYCN	Q0VAF6	AIP	Homo sapiens	O00170	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Optic Papillitis

Papillitis

Papilledema

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14069	SYCN Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SYCN	MGD	MGI:1915666
Canis familiaris	SYCN	VGNC	VGNC:47017
Bos taurus	SYCN	VGNC	VGNC:35507
Rattus norvegicus	SYCN	RGD	RGD:620862

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