Caspase 1 Activity Assay Kit 

Cysteine-dependent aspartate-directed proteases (Caspases) are a family of cysteine proteases that play important roles in apoptosis, necrosis, and inflammation. Sequential activation of caspases plays an important role in cell apoptosis. Caspase-1 (Interleukin 1β converting enzyme (ICE)) is an interleukin-1 converting enzyme that proteolytically cleaves the precursor protein of the inflammatory cytokines interleukin 18 and interleukin 1β into active forms, regulates apoptosis by shearing Bcl-XL and plays a key role in regulating host responses to inflammatory stimuli through its action on various cytokines.

MCE Caspase 1 Activity Assay Kit provides a simple and convenient way for detecting the activity of detection of Caspase 1 activity that based on the spectrophotometric. Caspase 1 catalyzes the substrate Ac-YVAD-pNA and produces yellow pNA, and the luminescence of the pNA is quantified using a spectrophotometer at 405 nm to determine the activity of Caspase 1.

-20°C, 1 year

Keep away from light