2. Academic Validation
  3. Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tü 6075. I. Taxonomy, fermentation, isolation and biological activities

Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tü 6075. I. Taxonomy, fermentation, isolation and biological activities

  • J Antibiot (Tokyo). 2002 Jun;55(6):565-70. doi: 10.7164/antibiotics.55.565.
Judith Schimana 1,  Klaus Gebhardt,  Alexandra Höltzel,  Dietmar G Schmid,  Roderich Süssmuth,  Johannes Müller,  Rüdiger Pukall,  Hans-Peter Fiedler
Affiliations

Affiliation

  • 1 Mikrobiologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany.
PMID: 12195962 DOI: 10.7164/antibiotics.55.565
Abstract

New lipopeptide Antibiotics, colourless arylomycins A series and yellow arylomycins B series were detected in the culture filtrate and mycelium extracts of Streptomyces sp. Tü 6075 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. Arylomycins are a family of lipohexapeptide Antibiotics, which represent the first examples of biaryl-bridged lipopeptides. They show Antibiotic activities against Gram-positive bacteria.

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