2. Academic Validation
  3. PD 116,152, a new phenazine antitumor antibiotic. Structure and antitumor activity

PD 116,152, a new phenazine antitumor antibiotic. Structure and antitumor activity

  • J Antibiot (Tokyo). 1986 Jun;39(6):800-3. doi: 10.7164/antibiotics.39.800.
T A Smitka,  R H Bunge,  J H Wilton,  G C Hokanson,  J C French,  C H He,  J Clardy
PMID: 3755428 DOI: 10.7164/antibiotics.39.800
Abstract

A new, highly substituted phenazine with antitumor activity was isolated from the culture broth of a Streptomyces sp. This compound, whose structure was determined by spectroscopic methods and verified by X-ray diffraction analysis, was found to be methyl 6-formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylate.

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