2. Metabolic Enzyme/Protease
  3. PAI-1
  4. MDI-2268

MDI-2268 is an inhibitor of plasma kallikrein inhibitor 1 (PAI-1). MDI-2268 has good antithrombotic properties and regulates blood coagulation and fibrinolysis process by enhancing fibrinolysis. MDI-2268 can be used in research areas such as deep vein thrombosis.

For research use only. We do not sell to patients.

MDI-2268 Chemical Structure

MDI-2268 Chemical Structure

CAS No. : 1609176-50-2

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10 mM * 1 mL in DMSO
ready for reconstitution
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MDI-2268 Related Antibodies

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Description

MDI-2268 is an inhibitor of plasma kallikrein inhibitor 1 (PAI-1). MDI-2268 has good antithrombotic properties and regulates blood coagulation and fibrinolysis process by enhancing fibrinolysis. MDI-2268 can be used in research areas such as deep vein thrombosis[1].

Molecular Weight

277.20

Formula

C10H10F3N3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NN)C(NCC1=CC=CC(OC(F)(F)F)=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 166.67 mg/mL (601.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6075 mL 18.0375 mL 36.0750 mL
5 mM 0.7215 mL 3.6075 mL 7.2150 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6075 mL 18.0375 mL 36.0750 mL 90.1876 mL
5 mM 0.7215 mL 3.6075 mL 7.2150 mL 18.0375 mL
10 mM 0.3608 mL 1.8038 mL 3.6075 mL 9.0188 mL
15 mM 0.2405 mL 1.2025 mL 2.4050 mL 6.0125 mL
20 mM 0.1804 mL 0.9019 mL 1.8038 mL 4.5094 mL
25 mM 0.1443 mL 0.7215 mL 1.4430 mL 3.6075 mL
30 mM 0.1203 mL 0.6013 mL 1.2025 mL 3.0063 mL
40 mM 0.0902 mL 0.4509 mL 0.9019 mL 2.2547 mL
50 mM 0.0722 mL 0.3608 mL 0.7215 mL 1.8038 mL
60 mM 0.0601 mL 0.3006 mL 0.6013 mL 1.5031 mL
80 mM 0.0451 mL 0.2255 mL 0.4509 mL 1.1273 mL
100 mM 0.0361 mL 0.1804 mL 0.3608 mL 0.9019 mL
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MDI-2268 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MDI-22681609176-50-2MDI2268MDI 2268PAI-1Plasminogen activator inhibitor-1Antithromboticblood clottinginhibitorInhibitorinhibit

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