2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Phlo1a

Phlo1a (μ-TrTx-Phlo1a) is a peptide toxin contains 35-amino acid residues. Phlo1b is a selective Nav1.7 inhibitor. Phlo1a has a weak inhibitory effect on Nav1.2 and Nav1.5.

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Phlo1a Chemical Structure

Phlo1a Chemical Structure

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Phlo1a Related Antibodies

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Nav1.1 Nav1.2 Nav1.3 Nav1.4 Nav1.5 Nav1.6 Nav1.7 Nav1.8

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Description

Phlo1a (μ-TrTx-Phlo1a) is a peptide toxin contains 35-amino acid residues. Phlo1b is a selective Nav1.7 inhibitor. Phlo1a has a weak inhibitory effect on Nav1.2 and Nav1.5[1].

IC50 & Target[1]

Nav1.7

 

Molecular Weight

4106.69

Formula

C178H262N52O49S6
Sequence

Ala-Cys-Arg-Glu-Leu-Leu-Gly-Gly-Cys-Ser-Lys-Asp-Ser-Asp-Cys-Cys-Ala-His-Leu-Glu-Cys-Arg-Lys-Lys-Trp-Pro-Tyr-His-Cys-Val-Trp-Asp-Trp-Thr-Ile-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys29)
Sequence Shortening

ACRELLGGCSKDSDCCAHLECRKKWPYHCVWDWTI-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys29)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Phlo1a Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phlo1aμ-TrTx-Phlo1aSodium ChannelNa channelsNa+ channelsNav1.7 inhibitorpeptide toxinInhibitorinhibitorinhibit

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