1. Immunology/Inflammation
  2. Interleukin Related
  3. Pyrazinib

Pyrazinib is a inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, inhibiting the secretion of Il-6, Il-4, Il-8 and Il-13 cytokines from in oac radioresistant cells. Pyrazinib inhibits blood vessel development in zebrafish.

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Pyrazinib Chemical Structure

Pyrazinib Chemical Structure

CAS No. : 200417-97-6

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Description

Pyrazinib is a inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, inhibiting the secretion of Il-6, Il-4, Il-8 and Il-13 cytokines from in oac radioresistant cells. Pyrazinib inhibits blood vessel development in zebrafish[1].

Molecular Weight

198.22

Formula

C12H10N2O

CAS No.
SMILES

OC(C=CC=C1)=C1/C=C/C2=NC=CN=C2

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pyrazinib
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HY-124613
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