Serpin E2 Protein, Mouse (HEK293, His, solution)

Serpin E2, a serine protease inhibitor, inhibits thrombin, trypsin, and urokinase, with a notable role in promoting neurite extension by specifically inhibiting thrombin.Its ability to bind heparin underscores interactions with glycosaminoglycans.The multifaceted inhibitory functions of Serpin E2 highlight its significance in regulating serine protease activities and potential impact on cellular processes, particularly in neurodevelopment.Serpin E2 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Serpin E2 protein, expressed by HEK293 , with C-10*His labeled tag.

Serpin E2, a serine protease inhibitor, exhibits inhibitory activity against thrombin, trypsin, and urokinase. Notably, it plays a role in promoting neurite extension by specifically inhibiting thrombin, emphasizing its involvement in neurodevelopmental processes. Additionally, Serpin E2 is recognized for its ability to bind heparin, showcasing its interaction with this important glycosaminoglycan. The multifaceted inhibitory functions of Serpin E2 underscore its significance in regulating serine protease activities and its potential impact on cellular processes, particularly in the context of neurodevelopment.

Mouse

HEK293

C-10*His

Q07235 (S20-P397)

20720  [NCBI]

SQFNSLSLEELGSNTGIQVFNQIIKSRPHENVVVSPHGIASILGMLQLGADGKTKKQLSTVMRYNVNGVGKVLKKINKAIVSKKNKDIVTVANAVFLRNGFKMEVPFAVRNKDVFQCEVQNVNFQDPASASESINFWVKNETRGMIDNLLSPNLIDGALTRLVLVNAVYFKGLWKSRFQPESTKKRTFVAGDGKSYQVPMLAQLSVFRSGSTRTPNGLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHITTKTIDSWMNTMVPKRMQLVLPKFTAVAQTDLKEPLKALGITEMFEPSKANFTKITRSESLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFSIRHNPTGAILFLGQVNKP

approximately 48 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.