1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. rU Phosphoramidite

rU Phosphoramidite  (Synonyms: DMT-2'O-TBDMS-rU phosphoramidite)

Cat. No.: HY-W048482 Purity: 99.22%
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rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

For research use only. We do not sell to patients.

rU Phosphoramidite Chemical Structure

rU Phosphoramidite Chemical Structure

CAS No. : 118362-03-1

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 g In-stock
5 g   Get quote  
10 g   Get quote  

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Description

rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

Molecular Weight

861.05

Formula

C45H61N4O9PSi

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC(C=C1)=O)N1[C@@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(N(C(C)C)C(C)C)OCCC#N)O[C@@H]2COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (116.14 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1614 mL 5.8069 mL 11.6137 mL
5 mM 0.2323 mL 1.1614 mL 2.3227 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.22%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1614 mL 5.8069 mL 11.6137 mL 29.0343 mL
5 mM 0.2323 mL 1.1614 mL 2.3227 mL 5.8069 mL
10 mM 0.1161 mL 0.5807 mL 1.1614 mL 2.9034 mL
15 mM 0.0774 mL 0.3871 mL 0.7742 mL 1.9356 mL
20 mM 0.0581 mL 0.2903 mL 0.5807 mL 1.4517 mL
25 mM 0.0465 mL 0.2323 mL 0.4645 mL 1.1614 mL
30 mM 0.0387 mL 0.1936 mL 0.3871 mL 0.9678 mL
40 mM 0.0290 mL 0.1452 mL 0.2903 mL 0.7259 mL
50 mM 0.0232 mL 0.1161 mL 0.2323 mL 0.5807 mL
60 mM 0.0194 mL 0.0968 mL 0.1936 mL 0.4839 mL
80 mM 0.0145 mL 0.0726 mL 0.1452 mL 0.3629 mL
100 mM 0.0116 mL 0.0581 mL 0.1161 mL 0.2903 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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rU Phosphoramidite
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