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(1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W890392
    (1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate

    		PROTAC Linkers Cancer
    (1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate is a PROTAC linker used in the synthesis of SMD-1087 (HY-170828) .
    (1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate
  • HY-170828
    SMD-1087

    		PROTACs SWI/SNF Complex Others
    SMD-1087 is a PROTAC that selectively targets SMARCA2 (DC50=8 nM, Dmax=89%) and SMARCA4 with a DC50 of 1 μM. SMD-1087 consists of the E3 ligase ligand (S,R,S)-AHPC-Me (blue part) (HY-112078), the target protein ligand SMI-1074 (red part) (HY-170817), and the PROTAC linker (1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate (black part) (HY-W890392). Among them, its target protein ligand + Linker part corresponds to SMARCA2 Ligand-Linker Conjugate-1 (HY-170829) .
    SMD-1087

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