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Results for "

1-Deoxy-D-xylulose 5-phosphate

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W717654
    1-Deoxy-D-xylulose 5-phosphate

    		Endogenous Metabolite Metabolic Disease
    1-Deoxy-D-xylulose 5-phosphate (DXP) is a biosynthetic precursor to isoprenoids, thiamin (vitamin B1), and pyridoxol (vitamin B6). 1-Deoxy-D-xylulose 5-phosphate can be utilized in metabolic research [1].
    1-Deoxy-D-xylulose 5-phosphate
  • HY-162898
    Antibacterial agent 242

    		Bacterial Infection
    Antibacterial agent 242 is a potent 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) inhibitor against Toxoplasma gondii with an IC50 value of 5.46 μM. Antibacterial agent 242 inhibits the activity of TgDXR enzyme and the proliferation of T. gondii in vitro [1].
    Antibacterial agent 242
  • HY-168447
    D-PheTrAP

    		Bacterial Infection
    D-PheTrAP is a bisubstrate analog inhibitor of 1-Deoxy-d-xylulose 5-phosphate synthase (DXPS). D-PheTrAP inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 μM, 2.1 μM, 2.4 μM, and 1.7 μM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively [1].
    D-PheTrAP
  • HY-134914
    Fosmidomycin

    		Antibiotic Parasite Infection
    Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model [1].
    Fosmidomycin
  • HY-158335
    DXR-IN-1

    		Parasite Infection
    DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity [1].
    DXR-IN-1

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