2. Anti-infection
  3. Bacterial
  4. D-PheTrAP

D-PheTrAP is a bisubstrate analog inhibitor of 1-Deoxy-d-xylulose 5-phosphate synthase (DXPS). D-PheTrAP inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 μM, 2.1 μM, 2.4 μM, and 1.7 μM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively.

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D-PheTrAP Chemical Structure

D-PheTrAP Chemical Structure

CAS No. : 2241298-26-8

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D-PheTrAP Related Antibodies

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Description

D-PheTrAP is a bisubstrate analog inhibitor of 1-Deoxy-d-xylulose 5-phosphate synthase (DXPS). D-PheTrAP inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 μM, 2.1 μM, 2.4 μM, and 1.7 μM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively[1].

Molecular Weight

367.29

Formula

C15H18N3O6P
CAS No.
SMILES

O=P(OCCC1=CN([C@H](CC2=CC=CC=C2)C(O)=O)N=N1)(O)C(C)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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D-PheTrAP Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-PheTrAP2241298-26-8BacterialDXPS inhibitorEcDXPSPaDXPSInhibitorinhibitorinhibit

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