2. Search Result
Search Result
Results for "

2-Oleoylglycerol

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W011121
    2-Oleoylglycerol

    2-OG

    		 GPR119 NF-κB TGF-beta/Smad GLP Receptor Metabolic Disease
    2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC50 value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the GPR119/TAK1/NF-κB/TGF-β1 signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) [2] .
    2-Oleoylglycerol
  • HY-121476
    Arachidonoyl Serinol

    		MAGL Neurological Disease
    Arachidonoyl Serinol, an endogenous cannabimimetic metabolite, is an inhibitor of monoacylglycerol lipase (MAGL). Arachidonoyl Serinol inhibits the hydrolysis of [ 3H]2-oleoylglycerol and [ 3H]anandamide with IC50s of ～70 μM [2] .
    Arachidonoyl Serinol
  • HY-N2512
    1-Monomyristin
    1 Publications Verification

    		 FAAH Bacterial Fungal Endogenous Metabolite Autophagy Infection
    1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans [2] .
    1-Monomyristin
  • HY-149507
    1,3-Capryloyl-2-oleoylglycerol

    		Endogenous Metabolite Others
    1,3-Capryloyl-2-oleoylglycerol is a triglyceride. 1,3-Capryloyl-2-oleoylglycerol has its hydroxyl groups at the 1 and 3 positions of glycerol acylated by Caprylic acid (HY-41417) and the hydroxyl group at the 2 position acylated by Oleic acid (HY-N1446) in its molecule .
    1,3-Capryloyl-2-oleoylglycerol
  • HY-131995
    O-Arachidonoyl glycidol

    		Cannabinoid Receptor Metabolic Disease
    O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 µM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 µM, respectively .
    O-Arachidonoyl glycidol
  • HY-137483
    Prostaglandin D2 serinol amide

    		Prostaglandin Receptor Endocrinology
    Prostaglandin D2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol .
    Prostaglandin D2 serinol amide
  • HY-118556
    Prostaglandin E2 serinol amide

    		Prostaglandin Receptor Endocrinology
    Prostaglandin E2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol. Prostaglandin E2 serinol amide is non-hydrolyzable to produce PGE2 and thus cannot inhibit leukotriene B4 biosynthesis, superoxide production, migration and antimicrobial peptide release .
    Prostaglandin E2 serinol amide
  • HY-W010667
    (Z)-2-(Oleoyloxy)propane-1,3-diyl dipalmitate

    1,3-Dipalmitoyl-2-Oleoylglycerol; ?1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)

    		 Endogenous Metabolite Metabolic Disease
    1,3-Dipalmitoyl-2-oleoyl glycerol (1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)) is a triacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 and sn-3 positions and oleic acid (HY-N1446) at the sn-2 position. It has been found in cocoa butter, Chinese tallow butter, and the palm stearin fraction of palm oil.
    (Z)-2-(Oleoyloxy)propane-1,3-diyl dipalmitate

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: