2. GPCR/G Protein Neuronal Signaling
  3. GPR119
  4. 2-Oleoylglycerol

2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo.

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2-Oleoylglycerol Chemical Structure

2-Oleoylglycerol Chemical Structure

CAS No. : 3443-84-3

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1 mg (28 mM * 100 μL in Ethanol) USD 60 In-stock
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5 mg (28 mM * 500 μL in Ethanol) USD 170 In-stock
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2-Oleoylglycerol Related Antibodies

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Description

2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo[1][2].

IC50 & Target

IC50: 2.5 μM (hGPR119) (in COS-7 cells)[1]
Molecular Weight

356.55

Formula

C21H40O4
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OCC(CO)OC(CCCCCCC/C=C\CCCCCCCC)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Purity & Documentation

Purity: ≥99.0%

COA (241 KB)

Handling Instructions (2659 KB)
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2-Oleoylglycerol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Oleoylglycerol3443-84-3GPR119G Protein-Coupled Receptor 119lipidCOS-7glucagon-likepeptide-1GLP-1Inhibitorinhibitorinhibit

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