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4-hydroxy Nonenal Mercapturic Acid

" in MedChemExpress (MCE) Product Catalog:

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Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136410
    4-hydroxy Nonenal Mercapturic Acid

    		Endogenous Metabolite Metabolic Disease
    4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.
    4-hydroxy Nonenal Mercapturic Acid
  • HY-W654214
    4-Hydroxy nonenal mercapturic acid-d3

    		Isotope-Labeled Compounds Others
    4-Hydroxy nonenal mercapturic acid-d3 is the deuterium labeled 4-Hydroxy nonenal mercapturic acid-d3 (HY-W654214) .
    4-Hydroxy nonenal mercapturic acid-d3

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