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AA-BR-157

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-168969
    AA-BR-157

    		PROTACs Cancer
    AA-BR-157 is a PROTAC degrader for metallothionein 2A (MT2A) with a DC50 of 190 nM. AA-BR-157 downregulates the cytoskeleton and cell motility regulating protein DIAPH3, inhibits the migration of MDA-MB-231 and U-87 MG. AA-BR-157 regulates the zinc homeostasis in MDA-MB-231 . (Pink: ligand for target protein MT2A ligand 1 (HY-168970); Black: linker (HY-119429); Blue: ligand for VHL E3 ligase (HY-125845))
    AA-BR-157
  • HY-168970
    MT2A ligand 1

    		Ligands for Target Protein for PROTAC Cancer
    MT2A ligand 1 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). MT2A ligand 1 can be used for synthesis AA-BR-157 (HY-168969) .
    MT2A ligand 1

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