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Azido-PEG4-Amido-Tris

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Intermediate (1) Fluorescent Dye (3) PROTAC Linkers (3) SARS-CoV (1)
By Research Areas:	Cancer (5) Infection (1)
Click Chemistry:	PROTAC Synthesis (3) Azide (3)

8

Inhibitors & Agonists

2

Fluorescent Dye

5

Peptides

3

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

**Azido-PEG4-Amido-Tris**	PROTAC Linkers	Cancer
Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-Tris is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane	PROTAC Linkers	Cancer
Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Ac-DEVD-AMC 4 Publications Verification	Fluorescent Dye	Others
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .

Ac-DEVD-AFC 5+ Cited Publications	Fluorescent Dye	Cancer
Ac-DEVD-AFC is a fluorogenic substrate (λ_ex=400 nm, λ_em=530 nm).

*Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle)* Azido-c(RGDyK)	Drug Intermediate	Others
Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) (Azido-c(RGDyK)) is a polypeptide composed of arginine, glycine, aspartic acid, and tyrosine that can be used for Synthesis of [ ¹⁸F]FPyKYNE-c(RGDyK) .

Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane	PROTAC Linkers	Cancer
Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

P315V3	SARS-CoV	Infection
P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC₅₀s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC₅₀ of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models .

Talogreptide mesaroxetan	Fluorescent Dye	Cancer
Talogreptide mesaroxetan is a diagnostic imaging agent, with antineoplastic effect .

Cat. No.	Product Name	Type

Ac-DEVD-AMC 4 Publications Verification	Chromogenic Substrates
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .

Ac-DEVD-AFC 5+ Cited Publications	Fluorescent Dyes/Probes
Ac-DEVD-AFC is a fluorogenic substrate (λ_ex=400 nm, λ_em=530 nm).

Cat. No.	Product Name	Target	Research Area

Ac-DEVD-AMC 4 Publications Verification	Fluorescent Dye	Others
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .

Ac-DEVD-AFC 5+ Cited Publications	Fluorescent Dye	Cancer
Ac-DEVD-AFC is a fluorogenic substrate (λ_ex=400 nm, λ_em=530 nm).

*Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle)* Azido-c(RGDyK)	Drug Intermediate	Others
Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) (Azido-c(RGDyK)) is a polypeptide composed of arginine, glycine, aspartic acid, and tyrosine that can be used for Synthesis of [ ¹⁸F]FPyKYNE-c(RGDyK) .

P315V3	SARS-CoV	Infection
P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC₅₀s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC₅₀ of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models .

Talogreptide mesaroxetan	Fluorescent Dye	Cancer
Talogreptide mesaroxetan is a diagnostic imaging agent, with antineoplastic effect .

Cat. No.	Product Name		Classification

**Azido-PEG4-Amido-Tris**		Azide PROTAC Synthesis
Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-Tris is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane		PROTAC Synthesis Azide
Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane		Azide PROTAC Synthesis
Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-amido-tri-(carboxyethoxymethyl)-methane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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