1. Anti-infection
  2. SARS-CoV
  3. P315V3

P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC50s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC50 of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

P315V3 Chemical Structure

P315V3 Chemical Structure

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Description

P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC50s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC50 of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models[1].

Molecular Weight

5443.22

Formula

C241H407N59O80S

Sequence

Val-Asp-Leu-Gly-Asp-Ile-Ser-Gly-Ile-Asn-Ala-Ser-Val-Val-Asn-Ile-Gln-Lys-Glu-Ile-Asp-Arg-Leu-Asn-Glu-Val-Ala-Lys-Asn-Leu-Asn-Glu-Ser-Leu-Ile-Asp-Leu-Gln-Glu-Leu-Gly-Ser-Gly-Ser-Gly-Cys-PEG4-(CH2CO2)-Cholesterol

Sequence Shortening

VDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGSGSGC-PEG4-(CH2CO2)-Cholesterol

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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P315V3
Cat. No.:
HY-P10872
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