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Results for "

LAMP1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

4

Recombinant Proteins

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163095

    Autophagy Neurological Disease
    RH1115 (compound 2c) is a modulator of the autophagy-lysosome. RH1115 induces changes to LAMP1 vesicle properties and alters lysosome positioning [1].
    RH1115
  • HY-RS07509

    Small Interfering RNA (siRNA) Others

    LAMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for LAMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    LAMP1 Human Pre-designed siRNA Set A
    LAMP1 Human Pre-designed siRNA Set A
  • HY-169363

    PD-1/PD-L1 Autophagy AUTACs Cancer
    PD-L1 degrader-2 (Compound B3) is an orally active AUTAC degrader, that degrades PD-L1 through autophagy-lysosome pathway with a DC50 of 0.5 μM. PD-L1 degrader-2 exhibits inhibitory activity against PD-1/PD-L1 interaction with an IC50 of 22.8 nM. PD-L1 degrader-2 upregulates the expressions of Atg9b, Lamp1 and Mitf, and activates the autophagy lysosome system. PD-L1 degrader- exhibits antitumor efficacy in CT26 mouse model [1]. (Pink: autophagy-lysosome activator (HY-159894); Black: linker (HY-W015088); Blue: PD-L1 ligand (HY-169365))
    PDL1 degrader-2

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