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Results for "

LNP

" in MedChemExpress (MCE) Product Catalog:

134

Inhibitors & Agonists

85

Biochemical Assay Reagents

2

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1

Natural
Products

2

Isotope-Labeled Compounds

118

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153852

    Liposome Others
    1LNP Lipid-7 (Compound 7013) is a lipid. LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) and for drug delivery .
    LNP Lipid-7
  • HY-154974

    Liposome Cancer
    LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model .
    LNP Lipid-8
  • HY-153186

    Liposome Others
    LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).
    LNP Lipid-3
  • HY-127105A
    Iptacopan hydrochloride
    5 Publications Verification

    LNP023 hydrochloride

    Complement System Metabolic Disease Inflammation/Immunology
    LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. LNP023 inhibits factor B with an IC50 value of 10 nM .
    Iptacopan hydrochloride
  • HY-153375

    Liposome Others
    LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
    LNP Lipid-5
  • HY-153376

    Liposome Others
    LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
    LNP Lipid-6
  • HY-153187

    Liposome Others
    LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances .
    LNP Lipid-4
  • HY-153136

    Liposome Others
    LNP Lipid-1 (Method B) is a lipid compound. LNP Lipid-1 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-1 has potential applications in the transport of biologically active substances such as small molecule agents, proteins, and nucleic acids .
    LNP Lipid-1
  • HY-142992

    Biochemical Assay Reagents Liposome Others
    LNP Lipid-2 is a lipid product can be used to deliver agents .
    LNP Lipid-2
  • HY-RS07729

    Small Interfering RNA (siRNA) Others

    LNP1 Human Pre-designed siRNA Set A contains three designed siRNAs for LNP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    LNP1 Human Pre-designed siRNA Set A
    LNP1 Human Pre-designed siRNA Set A
  • HY-127105
    Iptacopan
    5 Publications Verification

    LNP023

    Complement System Metabolic Disease Inflammation/Immunology
    Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G) .
    Iptacopan
  • HY-153231

    Fluorescent Dye Liposome Others
    eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
    eGFP mRNA-LNP
  • HY-153232

    Fluorescent Dye Liposome Others
    eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
    eGFP circRNA-LNP
  • HY-W590531

    Biochemical Assay Reagents Liposome Others
    80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .
    80-O16B
  • HY-153234

    CD19 Liposome Inflammation/Immunology Cancer
    CD19 car circRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car circRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car circRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
    CD19 car circRNA-LNP
  • HY-153235

    SARS-CoV Liposome Infection
    COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein , suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 Spike Protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 Spike Protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .
    COVID-19 Spike Protein mRNA-LNP
  • HY-153233

    CD19 Liposome Inflammation/Immunology Cancer
    CD19 car mRNA (Mouse)-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
    CD19 car mRNA (Mouse)-LNP
  • HY-160512

    Liposome Others
    Lipid 9 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
    Lipid 9
  • HY-160578

    N-Cholesteryl succinyl glucosamine

    Liposome Others
    Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .
    Glucosamine Cholesterol
  • HY-160553

    Liposome Others
    9322-O16B, an ionizable cationic lipid, is used for LNP generation .
    9322-O16B
  • HY-W590680

    Liposome Others
    ssPalmM is a SS-cleavable proton-activated lipid-like materials. ssPalmM can be used to form lipid nanoparticles (LNPs) for nuclear targeting of plasmid DNA .
    ssPalmM
  • HY-156630
    Ionizable lipid-1
    1 Publications Verification

    Liposome Others
    Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
    Ionizable lipid-1
  • HY-156630A

    Liposome Others
    Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
    Ionizable lipid-1 hydrochloride
  • HY-159735

    Liposome Others
    Lipid 23 is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNP). Lipid 23 can be used for mRNA delivery .
    Lipid 23
  • HY-149156

    Liposome Cancer
    Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
    Lipid C24
  • HY-153879

    Liposome Infection
    C12-TLRa is an adjuvant lipidoid. C12-TLRa acts as a structural component of LNP to enhance mRNA delivery. C12-TLRa substitution can increase antigen-specific antibody responses and B cell responses of clinically relevant mRNA-LNP vaccines .
    C12-TLRa
  • HY-W598178

    Liposome Others
    93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
    93-O17O
  • HY-143700

    Liposome Neurological Disease
    18:0 DAP can be used to formulate lipid nanoparticles (LNPs), which mRNA is encapsulated in their core .
    18:0 DAP
  • HY-159700

    Liposome Infection
    AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
    AA3-DLin
  • HY-160439

    Liposome Others
    Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construct lipid nanoparticles (LNPs) .
    Ionizable lipid-2
  • HY-148363

    Liposome Inflammation/Immunology
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
    Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate
  • HY-139305

    Liposome Cancer
    CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .
    CL4H6
  • HY-W590547

    Biochemical Assay Reagents Others
    (6-(4-Hydroxybutylamino)hexyl)carbamic undecyl is a lipid with a terminal hydroxyl group, which is used to construct or modify lipid nanoparticles (LNP). (6-(4-Hydroxybutylamino)hexyl)carbamic undecyl can be used in drug delivery research .
    (6-(4-Hydroxybutylamino)hexyl)carbamic undecyl
  • HY-138170
    ALC-0315
    10+ Cited Publications

    Liposome SARS-CoV Infection
    ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315
  • HY-112758
    DLin-KC2-DMA
    4 Publications Verification

    Liposome Others
    DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
    DLin-KC2-DMA
  • HY-138170A

    Liposome SARS-CoV Infection
    ALC-0315 Excipient is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 Excipient can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
    ALC-0315 (Excipient)
  • HY-151507

    Liposome Others
    306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
    306Oi10
  • HY-112763

    Liposome Inflammation/Immunology
    CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .
    CLinDMA
  • HY-160552

    Liposome Others
    244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
    244cis
  • HY-160579

    Liposome Others
    MIC5 is an LNP that can be used for vaccine delivery .
    MIC5
  • HY-147332

    Liposome Neurological Disease
    TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
    TCL053
  • HY-150116

    Liposome Others
    Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    Lipid 1
  • HY-150115

    Liposome Others
    Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    Lipid 10
  • HY-153378

    Liposome Others
    Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    Lipid 15
  • HY-150117

    Liposome Others
    Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    Lipid 6
  • HY-150118

    Liposome Others
    Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    Lipid 8
  • HY-134541
    SM-102
    Maximum Cited Publications
    16 Publications Verification

    Liposome Infection
    SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102
  • HY-134782

    Liposome Others
    OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
    OF-Deg-Lin
  • HY-134541A

    Liposome Infection
    SM-102 Excipient is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 Excipient has higher transfection efficiency. SM-102 Excipient plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
    SM-102 (Excipient)
  • HY-153377

    Liposome Inflammation/Immunology
    Lipid 14 is a potent ionizable lipid and can be used to synthesize lipid nanoparticles (LNPs) .
    Lipid 14

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