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  3. LNP Lipid-3

LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).

For research use only. We do not sell to patients.

LNP Lipid-3 Chemical Structure

LNP Lipid-3 Chemical Structure

CAS No. : 2648693-32-5

Size Price Stock Quantity
5 mg USD 430 In-stock
10 mg USD 700 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).

Molecular Weight

802.31

Formula

C50H95N3O4

CAS No.
Appearance

Liquid (Density: 0.95±0.1 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(C(CCCCCCCC)CCCCCC)OCCCCCCN(CCCCCCOC(C(CCCCCCCC)CCCCCC)=O)CCCN1C=NC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (124.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2464 mL 6.2320 mL 12.4640 mL
5 mM 0.2493 mL 1.2464 mL 2.4928 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2464 mL 6.2320 mL 12.4640 mL 31.1600 mL
5 mM 0.2493 mL 1.2464 mL 2.4928 mL 6.2320 mL
10 mM 0.1246 mL 0.6232 mL 1.2464 mL 3.1160 mL
15 mM 0.0831 mL 0.4155 mL 0.8309 mL 2.0773 mL
20 mM 0.0623 mL 0.3116 mL 0.6232 mL 1.5580 mL
25 mM 0.0499 mL 0.2493 mL 0.4986 mL 1.2464 mL
30 mM 0.0415 mL 0.2077 mL 0.4155 mL 1.0387 mL
40 mM 0.0312 mL 0.1558 mL 0.3116 mL 0.7790 mL
50 mM 0.0249 mL 0.1246 mL 0.2493 mL 0.6232 mL
60 mM 0.0208 mL 0.1039 mL 0.2077 mL 0.5193 mL
80 mM 0.0156 mL 0.0779 mL 0.1558 mL 0.3895 mL
100 mM 0.0125 mL 0.0623 mL 0.1246 mL 0.3116 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
LNP Lipid-3
Cat. No.:
HY-153186
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