1. Metabolic Enzyme/Protease
  2. Liposome
  3. Lipid 1

Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

For research use only. We do not sell to patients.

Lipid 1 Chemical Structure

Lipid 1 Chemical Structure

CAS No. : 2226547-17-5

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Liquid
1 mg In-stock
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg   Get quote  
200 mg   Get quote  

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Description

Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Molecular Weight

642.10

Formula

C42H79N3O

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CN(C)CCCC(NN(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (155.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5574 mL 7.7869 mL 15.5739 mL
5 mM 0.3115 mL 1.5574 mL 3.1148 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5574 mL 7.7869 mL 15.5739 mL 38.9347 mL
5 mM 0.3115 mL 1.5574 mL 3.1148 mL 7.7869 mL
10 mM 0.1557 mL 0.7787 mL 1.5574 mL 3.8935 mL
15 mM 0.1038 mL 0.5191 mL 1.0383 mL 2.5956 mL
20 mM 0.0779 mL 0.3893 mL 0.7787 mL 1.9467 mL
25 mM 0.0623 mL 0.3115 mL 0.6230 mL 1.5574 mL
30 mM 0.0519 mL 0.2596 mL 0.5191 mL 1.2978 mL
40 mM 0.0389 mL 0.1947 mL 0.3893 mL 0.9734 mL
50 mM 0.0311 mL 0.1557 mL 0.3115 mL 0.7787 mL
60 mM 0.0260 mL 0.1298 mL 0.2596 mL 0.6489 mL
80 mM 0.0195 mL 0.0973 mL 0.1947 mL 0.4867 mL
100 mM 0.0156 mL 0.0779 mL 0.1557 mL 0.3893 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lipid 1
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HY-150116
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