2. Metabolic Enzyme/Protease
  3. Liposome
  4. 113-O12B

113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA.

For research use only. We do not sell to patients.

113-O12B Chemical Structure

113-O12B Chemical Structure

CAS No. : 2803699-72-9

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Based on 1 publication(s) in Google Scholar

113-O12B Related Antibodies

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Description

113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA[1].

Molecular Weight

1223.03

Formula

C57H111N3O8S8
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(CCN(CCN(CCN(CCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O)C)CCC(OCCSSCCCCCCCC)=O)OCCSSCCCCCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (81.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8176 mL 4.0882 mL 8.1764 mL
5 mM 0.1635 mL 0.8176 mL 1.6353 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8176 mL 4.0882 mL 8.1764 mL 20.4410 mL
5 mM 0.1635 mL 0.8176 mL 1.6353 mL 4.0882 mL
10 mM 0.0818 mL 0.4088 mL 0.8176 mL 2.0441 mL
15 mM 0.0545 mL 0.2725 mL 0.5451 mL 1.3627 mL
20 mM 0.0409 mL 0.2044 mL 0.4088 mL 1.0221 mL
25 mM 0.0327 mL 0.1635 mL 0.3271 mL 0.8176 mL
30 mM 0.0273 mL 0.1363 mL 0.2725 mL 0.6814 mL
40 mM 0.0204 mL 0.1022 mL 0.2044 mL 0.5110 mL
50 mM 0.0164 mL 0.0818 mL 0.1635 mL 0.4088 mL
60 mM 0.0136 mL 0.0681 mL 0.1363 mL 0.3407 mL
80 mM 0.0102 mL 0.0511 mL 0.1022 mL 0.2555 mL
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113-O12B Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

113-O12B2803699-72-9LiposomemRNA vaccinesionizable cationic lipidoidInhibitorinhibitorinhibit

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