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LOXL3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Monoamine Oxidase (6) Small Interfering RNA (siRNA) (1)
By Research Areas:	Inflammation/Immunology (3)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

PXS-5153A monohydrochloride	Monoamine Oxidase	Inflammation/Immunology
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic *(LOXL2/LOXL3)* inhibitor, with an IC₅₀ of <40 nM for LOXL2 across all mammalian species and an IC₅₀ of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis.

PXS-6302 hydrochloride	Monoamine Oxidase	Inflammation/Immunology
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC₅₀s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .

PXS-4787 hydrochloride	Monoamine Oxidase	Others
PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC₅₀s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts .

LOXL3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LOXL3 Human Pre-designed siRNA Set A contains three designed siRNAs for LOXL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LOXL3 Human Pre-designed siRNA Set A LOXL3 Human Pre-designed siRNA Set A

PXS-5153A	Monoamine Oxidase	Inflammation/Immunology
PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic *(LOXL2/LOXL3)* inhibitor, with an IC₅₀ of <40 nM for LOXL2 across all mammalian species and an IC₅₀ of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.

PXS-4787	Monoamine Oxidase	Others
PXS-4787 is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 inhibits LOX with IC₅₀s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively .

PXS-6302	Monoamine Oxidase	Others
PXS-6302 is an irreversible lysyl oxidase inhibitor with IC₅₀s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .

Cat. No.	Compare	Product Name	Species	Source

	LOXL3 Protein, Human (sf9, GST) LOXL	Human	Sf9 insect cells
	LOXL3 Protein, Human (sf9, GST) is the recombinant human-derived LOXL3, expressed by Sf9 insect cells , with GST labeled tag. ,

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LOXL3 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
LOXL3 Human Pre-designed siRNA Set A contains three designed siRNAs for LOXL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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