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Results for "

PA1

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

3

Natural
Products

3

Recombinant Proteins

3

Isotope-Labeled Compounds

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139344
    FC-11

    		FAK PROTACs Cancer
    FC-11 is a PROTAC FAK degrader (DC90: 1 nM) . FC-11 contains CRBN ligand Pomalidomide (HY-10984), linker and FAK ligand PF562271 (HY-10459). FC-11 degrades FAK in various cells, with DC50s of 310 pM in TM3, 80 pM in PA1, 330 pM in MDA-MB-436, 370 pM in LNCaP, and 40 pM in Ramos cells [1].
    FC-11
  • HY-111915
    1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt

    18:1 PA

    		 Liposome Others
    1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (18:1 PA) is an anionic lipid that can be used to prepare liposomes, micelles and artificial membranes [1] .
    1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt
  • HY-W013549
    6-Aminopenicillanic acid

    6-APA

    		 Bacterial Infection
    6-Aminopenicillanic acid (6-APA) is an important precursor for the synthesis of -lactam antibiotics. 6-Aminopenicillanic acid is the main product of Penicillin G (PenG) hydrolyzed by penicillin acylase (PA) .
    6-Aminopenicillanic acid
  • HY-125667
    PA1

    Photoamiloride-1

    		 Sodium Channel Metabolic Disease
    PA1 is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 can switch to cis-PA1 at 400nm and trans-PA1 at 500nm. PA1 inhibits δ/αENaC, αβγENaC, and δβγENaC, with IC50 values of 4.3nM, 90 nM, and 390 nM, respectively [1].
    PA1
  • HY-P10352
    Pediocin PA 1

    		Bacterial Infection
    Pediocin PA-1 is a broad-spectrum lactic acid bacterial bacteriocin that inhibits the activity of foodborne pathogens such as Listeria monocytogenes and Gram-positive bacteria. Pediocin PA-1 can be used as a food biopreservative [1].
    Pediocin PA 1
  • HY-143407
    FAK-IN-3

    		FAK Cancer
    FAK-IN-3 (Compound 36) is a potent inhibitor of focal adhesion kinase (FAK). FAK-IN-3 not only decreases migration and invasion of PA-1 cells, but also reduces expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis, and no obvious adverse effects. FAK-IN-3 has the potential for the research of ovarian cancer [1].
    FAK-IN-3
  • HY-N9130
    Indicine

    		Others Others
    Indicine (Compound 3) is an alkaloid. Indicine can reduce pyrrolizine alkaloids (PA) .
    Indicine
  • HY-145486
    1-Arachidonoyl-sn-glycerol 3-phosphate ammonium

    20:4 Lyso PA

    		 Liposome Neurological Disease
    1-Arachidonoyl-sn-glycerol 3-phosphate ammonium (20:4 Lyso PA) is a phospholipid and an LPA derived from arachidonic acid. The concentration of 1-Arachidonoyl-sn-glycerol 3-phosphate ammonium in plasma is significantly correlated with the age of onset of cocaine use and the duration of abstinence. 1-Arachidonoyl-sn-glycerol 3-phosphate ammonium can be used in the research of biomarkers for cocaine use disorder (CUD) [1].
    1-Arachidonoyl-sn-glycerol 3-phosphate ammonium
  • HY-131574
    Heliosupine N-oxide

    		mAChR Neurological Disease
    Heliosupine N-oxide, Heliosupin metabolite, inhibits muscarinic acetylcholine receptor (mAChR) with the IC50 of 350 μM. Heliosupine N-oxide is a pyrrolizidine alkaloid (PA) .
    Heliosupine N-oxide
  • HY-128850S1
    N-Acetyl-D-mannosamine-13C

    N-Acetylmannosamine-13C; ManNAc-13C

    		 Bacterial Neurological Disease
    N-Acetyl-D-mannosamine- 13C is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
    N-Acetyl-D-mannosamine-13C
  • HY-128850S5
    N-Acetyl-D-mannosamine-15N

    N-Acetylmannosamine-15N; ManNAc-15N

    		 Isotope-Labeled Compounds Bacterial Neurological Disease
    N-Acetyl-D-mannosamine- 15N is the 15N labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
    N-Acetyl-D-mannosamine-15N
  • HY-146327
    PqsR/LasR-IN-1

    		Bacterial Antibiotic Infection
    PqsR/LasR-IN-1 (compound 2a) is a potent PqsR and LasR systems inhibitor. PqsR/LasR-IN-1 has anti-virulence activity against Pseudomonas aeruginosa. PqsR/LasR-IN-1 can reduce production of biofilm, pyocyanin, and rhamnolipids in PA .
    PqsR/LasR-IN-1
  • HY-128850S2
    N-Acetyl-D-mannosamine-13C-1

    N-Acetylmannosamine-13C-1; ManNAc-13C-1

    		 Isotope-Labeled Compounds Bacterial Neurological Disease
    N-Acetyl-D-mannosamine- 13C-1 is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
    N-Acetyl-D-mannosamine-13C-1
  • HY-W013549R
    6-Aminopenicillanic acid (Standard)

    		Drug Metabolite Bacterial Infection
    6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is an important precursor for the synthesis of ?-lactam antibiotics. 6-Aminopenicillanic acid is the main product of Penicillin G (PenG) hydrolyzed by penicillin acylase (PA) .
    6-Aminopenicillanic acid (Standard)

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