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Selenium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) Autophagy (1) Biochemical Assay Reagents (2) Endogenous Metabolite (5) Fluorescent Dye (2) Fungal (1) Isotope-Labeled Compounds (2) NF-κB (1) NO Synthase (1) Parasite (1) Reactive Oxygen Species (1) TNF Receptor (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Endocrinology (1) Infection (2) Inflammation/Immunology (4) Metabolic Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-150287

*Insulin-Transferrin-Selenium, 100X* 2 Publications Verification ITS-G	Biochemical Assay Reagents	Endocrinology
Insulin-Transferrin-Selenium, 100X (ITS-G) is a mixture of Insulin, transferrin, and sodium selenite that is a general supplement designed for use in classic media such as DMEM, RPMI-1640, and nutrient media such as Ham's F-12, DMEM/F-12 . Insulin-Transferrin-Seleniu is added to basal medium to reduce the amount of fetal calf serum required to culture cells.

HY-B1000A

L-SelenoMethionine 2 Publications Verification	Endogenous Metabolite Apoptosis	Cancer
L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-B1000

Selenomethionine 4 Publications Verification Seleno-DL-methionine; DL-Selenomethionine	Autophagy Endogenous Metabolite	Cancer
Selenomethionine is a naturally occurring amino acid containing selenium and is a common natural food source.

HY-D0073

2,3-Diaminonaphthalene	Fluorescent Dye	Others
2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium ion detection and also used for the fluorometric determination of nitrite.

HY-163080S

Selenium-77 ⁷⁷Se	Isotope-Labeled Compounds	Others
Selenium-77 (77Se) is a stable (non-radioactive) isotope of Selenium. Selenium-77 is both naturally occurring and produced by fission.

HY-117429

Se-Aspirin Selenium-acetylsalicylic acid	NF-κB	Inflammation/Immunology
Se-Aspirin is a hybrid molecule of selenium and Aspirin (HY-14654). Se-Aspirin reduces the viability of cancer cell lines, particularly colorectal cancer cells .

HY-156558

SeGalNac	Endogenous Metabolite	Metabolic Disease
SeGalNac is a selenium metabolite found in human urine. SeGalNac can be used in the study of selenoglucose metabolism .

HY-W585825

Selenoethionine	Endogenous Metabolite	Others
Selenoethionine is a selenium-containing amino acid .

HY-B1000AR

L-SelenoMethionine (Standard)	Endogenous Metabolite Apoptosis	Cancer
L-SelenoMethionine (Standard) is the analytical standard of L-SelenoMethionine. This product is intended for research and analytical applications. L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-151188

DHU-Se1	NO Synthase TNF Receptor	Inflammation/Immunology
DHU-Se1 is a potent anti-inflammatory agent. DHU-Se1 can stimulate macrophages to release the reactive selenium compound and reduce the expression of cellular inflammatory factors (eg: iNOS and TNF-α). DHU-Se1 alleviate the process of inflammation by blocking the polarization of macrophages from M0 to M1 .

HY-W017224

Sodium butane-1-sulfonate Sodium 1-butanesulfonate	Biochemical Assay Reagents	Others
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) can be used as a mobile phase to separate arsenic or selenium compounds .

HY-129960S

L-Selenocystine-77Se2	Isotope-Labeled Compounds	Others
Selenocystine-77Se2 is a stable isotope labelled amino acid. L-Selenocystine is a diselenide-bridged amino acid. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions.

HY-112549

5-oxo-ETE 5-KETE	Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
5-oxo-ETE is a potent chemoattractant for eosinophils. 5-oxo-ETE inhibits selenium-induced apoptosis in prostate cancer cells. 5-oxo-ETE can be used in research into asthma, allergic diseases, cancer and cardiovascular disease .

HY-159004

Se-DOPE	Reactive Oxygen Species	Metabolic Disease Inflammation/Immunology
Se-DOPE is a phospholipid molecule with selenium. Se-DOPE can be used to synthesize the bifunctional Janus liposozyme. Se-DOPE promotes the production of ROS with induction of lights, scavenges the ROS with the presence of glutathione. Se-DOPE regulates redox and immune homeostasis in infected diabetic wounds .

HY-158616

4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one	Fluorescent Dye	Others
4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one (compound 2f) is a selenol fluorescent probe designed based on a nucleophilic aromatic substitution mechanism. It can selectively recognize selenols in neutral aqueous solution without significant interference from biological thiols, amines or alcohols. It can be used to quantify the selenium content in selenoenzymes and to image the activity of endogenous selenols in living cells.

HY-146464

Antifungal agent 30	Fungal	Infection
Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51 .

HY-159915

Se2h	Parasite	Infection
Se2h is a cruzain inhibitor that exhibits strong activity against the intracellular amastigotes of Trypanosoma cruzi (EC₅₀ < 1 μM, SI > 10), with an inhibitory activity against cruzain of IC₅₀ < 100 nM (SI > 5.55). Compared to Benznidazole (HY-B1548) and the cruzain inhibitor K777 (HY-119293), Se2h shows superior selectivity and inhibition, while its selenazole structure reduces selenium-related toxicity. Se2h exhibits antiparasitic activity and holds promise for research in Chagas disease .

Cat. No.	Product Name	Type

HY-D0073

2,3-Diaminonaphthalene	Fluorescent Dyes/Probes
2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium ion detection and also used for the fluorometric determination of nitrite.

HY-158616

4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one	Dyes
4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one (compound 2f) is a selenol fluorescent probe designed based on a nucleophilic aromatic substitution mechanism. It can selectively recognize selenols in neutral aqueous solution without significant interference from biological thiols, amines or alcohols. It can be used to quantify the selenium content in selenoenzymes and to image the activity of endogenous selenols in living cells.

4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one

Dyes

4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one (compound 2f) is a selenol fluorescent probe designed based on a nucleophilic aromatic substitution mechanism. It can selectively recognize selenols in neutral aqueous solution without significant interference from biological thiols, amines or alcohols. It can be used to quantify the selenium content in selenoenzymes and to image the activity of endogenous selenols in living cells.

Cat. No.	Product Name	Type

HY-150287

*Insulin-Transferrin-Selenium, 100X* 2 Publications Verification ITS-G	Microbial Culture
Insulin-Transferrin-Selenium, 100X (ITS-G) is a mixture of Insulin, transferrin, and sodium selenite that is a general supplement designed for use in classic media such as DMEM, RPMI-1640, and nutrient media such as Ham's F-12, DMEM/F-12 . Insulin-Transferrin-Seleniu is added to basal medium to reduce the amount of fetal calf serum required to culture cells.

HY-W017224

Sodium butane-1-sulfonate Sodium 1-butanesulfonate	Surfactants
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) can be used as a mobile phase to separate arsenic or selenium compounds .

Cat. No.	Product Name	Target	Research Area

HY-129960

L-Selenocystine	Peptides	Others
L-Selenocystine is a diselenide-bridged amino acid. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1000A

L-SelenoMethionine 2 Publications Verification	Structural Classification Microorganisms other families Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-B1000

Selenomethionine 4 Publications Verification Seleno-DL-methionine; DL-Selenomethionine	Structural Classification Microorganisms Classification of Application Fields Source classification Disease markers Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer	Autophagy Endogenous Metabolite
Selenomethionine is a naturally occurring amino acid containing selenium and is a common natural food source.

HY-156558

SeGalNac	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
SeGalNac is a selenium metabolite found in human urine. SeGalNac can be used in the study of selenoglucose metabolism .

HY-B1000AR

L-SelenoMethionine (Standard)	Structural Classification Microorganisms other families Animals Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Endogenous Metabolite Apoptosis
L-SelenoMethionine (Standard) is the analytical standard of L-SelenoMethionine. This product is intended for research and analytical applications. L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

Species:	Human (2) Mouse (1)
Tag:	His (3)
Source:	HEK293 (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P71935A

	FABP1/L-FABP Protein, Mouse (His) Fabp1; FabplFatty acid-binding protein; liver; 14 kDa Selenium-binding protein; Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP	Mouse	E. coli
	FABP1/L-FABP Protein facilitates cholesterol uptake in hepatocytes via lipoproteins, binding cholesterol, free fatty acids, coenzyme A derivatives, bilirubin, and small molecules within the cytoplasm. It may also participate in intracellular lipid transport processes. FABP1/L-FABP Protein, Mouse (His) is the recombinant mouse-derived FABP1/L-FABP protein, expressed by E. coli , with N-6*His labeled tag. The total length of FABP1/L-FABP Protein, Mouse (His) is 127 a.a., with molecular weight of ~15 kDa.

HY-P71145

	PRDX6 Protein, Human (His) Peroxiredoxin-6; 1-Cys Peroxiredoxin; 1-Cys PRX; 24 kDa Protein; Acidic Calcium-Independent Phospholipase A2; aiPLA2; Antioxidant Protein 2; Liver 2D PAGE Spot 40; Non-Selenium Glutathione Peroxidase; NSGPx; Red Blood Cells Page Spot 12; PRDX6; AOP2; KIAA0106	Human	E. coli
	The PRDX6 protein is a thiol-specific peroxidase that plays a crucial role in cellular defense against oxidative stress. It catalyzes the reduction of hydrogen peroxide and various organic hydroperoxides to water and alcohols. PRDX6 Protein, Human (His) is the recombinant human-derived PRDX6 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PRDX6 Protein, Human (His) is 224 a.a., with molecular weight of 30-33 kDa.

HY-P71291

	SEPHS1 Protein, Human (HEK293, His) Selenide; water dikinase 1; Selenium donor protein 1; Selenophosphate synthase 1; SEPHS1; SELD; SPS; SPS1	Human	HEK293
	The SEPHS1 protein catalyzes the synthesis of selenophosphate, a key step in selenium metabolism involving the conversion of selenide and ATP.This enzyme activity is the basis for selenoprotein biosynthesis and effectively promotes the incorporation of selenium into selenocysteine.SEPHS1 Protein, Human (HEK293, His) is the recombinant human-derived SEPHS1 protein, expressed by HEK293 , with C-6*His labeled tag.

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