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YTHDF2-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173008
    YTHDF2-IN-1

    		Epigenetic Reader Domain Apoptosis Cancer
    YTHDF2-IN-1 (Compound CK-75) is the inhibitor for YT521-B homology domain family 2 YTHDF2 (Kd=26.2 μM), that blocks the interaction between YTHDF2 and m6A RNA. YTHDF2-IN-1 inhibits the colony formation of JAR cells, exhibits antiproliferative activity in a variety of cancer cells (IC50 in micromolar levels), arrests the cell cycle at G0/G1 phase, induces apoptosis in K562 .
    YTHDF2-IN-1

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