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Results for "

activities of peptidases

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dipeptidyl Peptidase (21) Amino Acid Derivatives (1) Aminopeptidase (1) Angiotensin-converting Enzyme (ACE) (1) Apoptosis (7) Aryl Hydrocarbon Receptor (1) Bacterial (2) Biochemical Assay Reagents (2) Deubiquitinase (2) Endogenous Metabolite (1) Estrogen Receptor/ERR (1) Ferroptosis (6) Fluorescent Dye (4) Glutathione Peroxidase (1) Glycosidase (2) HIV (1) Interleukin Related (1) Isotope-Labeled Compounds (4) mGluR (1) Mitophagy (1) Phospholipase (1) PPAR (1) Proteasome (2) Reactive Oxygen Species (1) Ser/Thr Protease (3) TNF Receptor (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (2) Endocrinology (1) Infection (5) Inflammation/Immunology (4) Metabolic Disease (19) Neurological Disease (4)

By Targets:

Dipeptidyl Peptidase (21)

Amino Acid Derivatives (1)

Aminopeptidase (1)

Angiotensin-converting Enzyme (ACE) (1)

Apoptosis (7)

Aryl Hydrocarbon Receptor (1)

Bacterial (2)

Biochemical Assay Reagents (2)

Deubiquitinase (2)

Endogenous Metabolite (1)

Estrogen Receptor/ERR (1)

Ferroptosis (6)

Fluorescent Dye (4)

Glutathione Peroxidase (1)

Glycosidase (2)

HIV (1)

Interleukin Related (1)

Isotope-Labeled Compounds (4)

mGluR (1)

Mitophagy (1)

Phospholipase (1)

PPAR (1)

Proteasome (2)

Reactive Oxygen Species (1)

Ser/Thr Protease (3)

TNF Receptor (1)

By Research Areas:

Cancer (11)

Cardiovascular Disease (2)

Endocrinology (1)

Infection (5)

Inflammation/Immunology (4)

Metabolic Disease (19)

Neurological Disease (4)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Dipeptidyl Peptidase Proteolytic Enzyme Nuclear Factor of activated T Cells (NFAT)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4920

Mca-SEVNLDAEFK(Dnp)-NH2	Fluorescent Dye	Others
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 .

HY-P4470

Phe-Pro-Ala-pNA	Ser/Thr Protease	Cancer
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .

HY-137834

Gly-Pro-AMC hydrobromide 1 Publications Verification	Fluorescent Dye	Others
Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .

HY-P4460

AAA-pNA	Ser/Thr Protease	Cancer
AAA-pNA is a chromogenic substrate of *Tripeptidyl-peptidase* II*. AAA-pNA can be used to test Tripeptidyl-peptidase* II activity .

HY-P4464

Ala-Phe-Pro-pNA	Ser/Thr Protease	Cancer
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .

HY-163335

MPO-IN-7	Glutathione Peroxidase Dipeptidyl Peptidase Glycosidase	Cardiovascular Disease Inflammation/Immunology
MPO-IN-7 (compound MDC) is a myeloperoxidase inhibitor with the IC₅₀ values of 41 μM, 25 μM and 4.5 μM towards α-Glucosidase, dipeptidyl peptidase-4 and myeloperoxidase, respectively. MPO-IN-7 shows antioxidant and anti-inflammatory activity in vitro .

HY-P4488

H-Pro-Pro-Gln-OH	Dipeptidyl Peptidase	Others
H-Pro-Pro-Gln-OH is a oligopeptide with excellent *dipeptidyl peptidase-IV (DPP-IV)* inhibitory activity .

HY-155704

Lyciumamide A	PPAR	Others
DPP-IV-IN-5 is isolated from the fruits of Lycium barbarum. DPP-IV-IN-5 exerts moderate agonistic activities for peroxisome proliferator-activated receptor (PPARγ) with EC₅₀ values of 10.09 - 44.26 μM and also presents inhibitory activity on dipeptidyl peptidase-4 (DPPIV) with an IC₅₀ value of 47.13 μM .

HY-148190

Sheng Gelieting CGT-8012	Dipeptidyl Peptidase	Endocrinology
Sheng Gelieting (CGT-8012) is a *dipeptidy peptidase-IV enzyme (DP-IV)* inhibitor. Sheng Gelieting has great DP-IV inhibition activity with an IC₅₀ value of 87 nM. Sheng Gelieting can be used for curing or preventing diseases relevant to the dipeptidy peptidase-IV enzyme, such as the diabetes, particularly the II-type diabete .

HY-W764737

Methylboronic acid pinacol ester-d3	Isotope-Labeled Compounds	Cancer
Methylboronic acid pinacol ester is an orally administered compound that inhibits the activity of peptidases and imidazole derivatives. Methylboronic acid pinacol ester is used as a medicinal preparation for cancer .

HY-E70018

Picornain 3C	Endogenous Metabolite	Infection Metabolic Disease
Picornain 3C is a protease found in picornaviruses, which cleaves peptide bonds of non-terminal sequences. Picornain 3C is an intermediate between the serine peptidase chymotrypsin and the cysteine peptidase papain. Picornain 3C shows endopeptidase activity by selectively cleaving Gln-Gly bonds in the polyprotein of poliovirus and with substitution of Glu for Gln, and Ser or Thr for Gly in other picornaviruses .

HY-W010955

Z-Phe-Leu-OH NSC 334018	Biochemical Assay Reagents	Others
Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity .

HY-N4069

Lupinalbin A Boeravinone L	Estrogen Receptor/ERR Aryl Hydrocarbon Receptor Dipeptidyl Peptidase Glycosidase	Metabolic Disease
Lupinalbin A (Boeravinone L) is a dipeptidyl peptidase 4 (DPP4) and α-glucosidase inhibitor with IC₅₀ values of 45.2 and 53.4 µM, respectively. Lupinalbin A exhibits antidiabetic activity .

HY-P3985

Bradykinin potentiator B Bradykinin potentiating peptide B	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease Others
Bradykinin potentiator B (Bradykinin potentiating peptide B) is venom of Agkistrodon halys blomhoffi. Bradykinin potentiator B is a potent ACE inhibitor. Bradykinin potentiator inhibits the activity of bradykinin inhibitory peptidase .

HY-157390

DPP-4-IN-9	Dipeptidyl Peptidase	Metabolic Disease
DPP-4-IN-9 (compound 6l) is a potent inhibitor of dipeptidyl peptidase DPP-4 (IC₅₀: 8.22 nM). DPP-4-IN-9 has antihyperglycemic activity .

HY-137164A

Ala-Ala-Phe-AMC TFA	Fluorescent Dye	Others
Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .

HY-146455

DPP-4-IN-3	Dipeptidyl Peptidase Reactive Oxygen Species	Metabolic Disease
DPP-4-IN-3 (Compound 5a) is a potent *dipeptidyl peptidase* IV (DPP-IV) inhibitor with an IC₅₀** of 0.75 nM. DPP-4-IN-3 shows excellent antioxidant and insulinotropic activity .

HY-14291

Vildagliptin 4 Publications Verification LAF237; NVP-LAF 237	Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease Cancer
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-N10064

Ficusonolide	Others	Metabolic Disease
Ficusonolide has significant antidiabetic activity with a possible mechanism of interaction with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.

HY-12480

Lanopepden GSK 1322322	Bacterial	Infection
Lanopepden (GSK 1322322) is a peptidyl peptidase (PDF) inhibitor. Lanopepden inhibits PDF activity, preventing bacterial protein synthesis, thereby exerting antibacterial activity. Lanopepden is primarily effective against Gram-positive bacteria. Lanopepden is used in the study of acute bacterial skin and skin structure infections .

HY-14291S1

Vildagliptin-d7 LAF237-d₇; NVP-LAF 237-d₇	Isotope-Labeled Compounds Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease
Vildagliptin-d₇ is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].

HY-14291A

Vildagliptin dihydrate LAF237 dihydrate; NVP-LAF 237 dihydrate	Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease Cancer
Vildagliptin dihydrate (LAF237 dihydrate) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin dihydrate possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-14291S

Vildagliptin-d3 LAF237-d₃; NVP-LAF 237-d₃	Isotope-Labeled Compounds Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease
Vildagliptin-d₃ is the deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1][2].

HY-158412

BT317	Proteasome Apoptosis	Cancer
BT317 is a blood-brain transmissible mitochondrial Lon peptidase I (LonP1) and CT-L proteasome inhibitor. BT317 can increase the production of reactive oxygen species (ROS) and induce apoptosis in astrocytoma cells. BT317 has antitumor activity .

HY-15981

Omarigliptin MK-3102	Dipeptidyl Peptidase	Neurological Disease Metabolic Disease
Omarigliptin (MK-3102) is a potent, selective, orally active and cross the blood-brain barrier *dipeptidyl peptidase* 4 (DPP-4)** inhibitor. Omarigliptin shows anti-parkinsonian activity. Omarigliptin has the neuroprotective effect to improve diabetes-associated cognitive dysfunction .

HY-W699926

(R)-Naproxen acyl-β-D-glucuronide (R)-Naproxen-β-D-glucuronide	Biochemical Assay Reagents
(R)-Naproxen acyl-β-D-glucuronide ((R)-Naproxen-β-D-glucuronide) is a compound metabolite with anti-inflammatory activity. (R)-Naproxen acyl-β-D-glucuronide can serve as a sensitive fluorescent substrate for proglutamyl peptidase 1, which produces a blue reaction after cleavage.

HY-N8134

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one	Dipeptidyl Peptidase	Metabolic Disease
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with *dipeptidyl peptidase-4 (DPP-4)* and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities .

HY-14291R

Vildagliptin (Standard)	Dipeptidyl Peptidase Ferroptosis Apoptosis	Metabolic Disease
Vildagliptin (Standard) is the analytical standard of Vildagliptin. This product is intended for research and analytical applications. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-P5296

Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans	Fluorescent Dye	Others
Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a fluorophore Dabsyl-labeled peptide. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans can be used to test the peptidase activity of the LasA protease of Pseudomonas aeruginosa. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans has enzyme specificity and has application value .

HY-18522

AA26-9	Phospholipase	Metabolic Disease
AA26-9 is a potent and broad spectrum serine hydrolase inhibitor. AA26-9 targets included serine peptidases, lipases, amidases, esterases, and thioesterases. AA26-9 shows inhibitory activity against approximately 1/3 of the 40+ serine hydrolases detected in immortalized T cell lines .

HY-14291B

(2R)-Vildagliptin (2R)-LAF237; (2R)-NVP-LAF 237	Others	Metabolic Disease
(2R)-Vildagliptin is the isomer of Vildagliptin (HY-14291), and can be used as an experimental control. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-20841

Boc-(2S)-Gly-4-pyranoyl (S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-Pyranoyl-Gly-OH	Amino Acid Derivatives	Others
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .

HY-120631A

BMS-538305 hydrochloride	Others	Others
BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.

HY-15981R

Omarigliptin (Standard)	Dipeptidyl Peptidase	Neurological Disease Metabolic Disease
Omarigliptin (Standard) is the analytical standard of Omarigliptin. This product is intended for research and analytical applications. Omarigliptin (MK-3102) is a potent, selective, orally active and cross the blood-brain barrier *dipeptidyl peptidase* 4 (DPP-4)** inhibitor. Omarigliptin shows anti-parkinsonian activity. Omarigliptin has the neuroprotective effect to improve diabetes-associated cognitive dysfunction .

HY-130553

β-Spaglumic acid β-NAAG; β-N-Acetylaspartylglutamic acid	Aminopeptidase mGluR	Neurological Disease
β-Spaglumic acid (β-NAAG) is a competitive NAAG peptidase inhibitor (K_i=1 µM) that protects spinal cord neurons from excitotoxicity and hypoxic damage. β-Spaglumic acid is also a selective mGluR3 antagonist (mGluR3 receptor functions to regulate activity-dependent synaptic potentiation in the hippocampus). β-Spaglumic acid can be used in neuroprotection-related studies .

HY-100900

ML364 10+ Cited Publications	Deubiquitinase	Cancer
ML364 is a selective *ubiquitin specific peptidase* 2 (USP2) inhibitor (IC₅₀*=1.1 μM) with anti-proliferative activity, which direct binds to USP2 (K_d*=5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP .

HY-U00346A

TS-021	Dipeptidyl Peptidase	Metabolic Disease
TS-021 is a selective, orally active, reversible and long-acting DPP-IV inhibitor, and exhibits significant inhibition selectivity against DPP-8 (> 600 fold), DPP-9 (> 1200 fold) and other peptidases (> 15,000 fold). TS-021 inhibits DPP-IV activity in human plasma with an IC₅₀ value of 5.34 nM. TS-021 has long-term persistent plasma drug concentration and potent antihyperglycemic activity, and increases in the active form of GLP-1 .

HY-13233A

Talabostat mesylate Maximum Cited Publications 35 Publications Verification Val-boroPro mesylate; PT100 mesylate	Dipeptidyl Peptidase	Inflammation/Immunology Cancer
Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective *dipeptidyl peptidase* IV (DPP-IV) inhibitor (IC₅₀ < 4 nM; K_i = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) (IC₅₀ = 560 nM), inhibits DPP8/9 (IC₅₀ = 4/11 nM; K_i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC₅₀** = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities .

HY-14292

NVP-DPP728	Dipeptidyl Peptidase	Metabolic Disease
NVP-DPP728 is a potent, reversible and nitrile-dependent *dipeptidyl peptidase* IV (DPP-IV)** inhibitor. NVP-DPP728 can inhibit human DPP-IV amidolytic activity with a K_i of 11 nM. NVP-DPP728 inhibits degradation of glucagon-like peptide-1 (GLP-1) and thereby potentiates insulin release in response to glucose intake. NVP-DPP728 can be used for researching diabetes .

HY-151871

ICeD-2	Dipeptidyl Peptidase HIV	Infection
ICeD-2 is a inducer of cell death, can induce HIV-1 infected cell kill. ICeD-2-mediated HIV-1 infected cell kill is dependent on HIV-1 protease activity. ICeD-2 potently blocks hydrolysis of Gly-Pro-AMC by *dipeptidyl peptidase* DPP8 and DPP9**. ICeD-2 shows strong stabilization of DPP9 in PBMCs .

HY-129407

AAF-CMK TFA Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II	Proteasome	Infection
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

HY-13233

Talabostat Val-boroPro; PT100	Dipeptidyl Peptidase	Inflammation/Immunology Cancer
Talabostat (Val-boroPro; PT100) is an orally active and nonselective *dipeptidyl peptidase* IV (DPP-IV) inhibitor (IC₅₀ < 4 nM; K_i = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC₅₀ = 560 nM), inhibits DPP8/9 (IC₅₀ = 4/11 nM; K_i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC₅₀** = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities .

HY-14291S2

Vildagliptin-13C5,15N LAF237-¹³C₅,¹⁵N; NVP-LAF 237-¹³C₅,¹⁵N	Isotope-Labeled Compounds Dipeptidyl Peptidase Apoptosis Ferroptosis	Metabolic Disease
Vildagliptin- ¹³C₅, ¹⁵N (LAF237- ¹³C₅, ¹⁵N; NVP-LAF 237- ¹³C₅, ¹⁵N) is a ¹³C- and ¹⁵N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC₅₀ of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .

HY-P10416

Q14 Q14 peptide	Deubiquitinase Mitophagy	Others Neurological Disease
Q14 is a polypeptide derived from the USP30 (ubiquitin specific peptidase 30) transmembrane (TM) domain with the ability to inhibit the deubiquitination activity of USP30 (IC₅₀=57.2 nM). Q14 reduces USP30 activity by inhibiting the interaction between the USP30 transmembrane domain and its catalytic domain. Q14 peptide contains the LC3 interaction region (LIR) motif, which enables it to bind to the LC3 and accelerate the formation of autophagosomes, thereby promoting mitophagy. Q14 can be used in the study of neurodegenerative diseases as well as mitochondrial quality control and cell metabolism .

HY-155027

DPP-4-IN-8	Dipeptidyl Peptidase TNF Receptor Interleukin Related	Inflammation/Immunology Cancer
DPP-4-IN-8 (compound 27) is a potent and selective DPP4 (dipeptidyl peptidase 4) inhibitor, with a K_i of 0.96 μM. DPP-4-IN-8 blocks the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells. DPP-4-IN-8 also dose-dependently suppresses the expression levels of the chemokines tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β) .

HY-167680

Denagliptin GSK823093	Others	Metabolic Disease
Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings .

HY-168729

Antibacterial agent 256	Bacterial	Infection
Antibacterial agent 256 (Compound C09) is an inhibitor for type I signal peptidase (SPase I). Antibacterial agent 256 inhibits gram-positive bacteria, that inhibits S. aureus ATCC 29213, E. faecium QF31, E. faecalis SF23-1 and S. suis P1/7, with MIC of 1-16 μg/mL. Antibacterial agent 256 exhibits cytotoxicity in cancer cell HEp-2 and Caco-2 with CC₅₀ of 14.65 μg/mL and 21.93 μg/mL. Antibacterial agent 256 exhibits a hemolytic activity on mouse RBCs, with an HC₅₀ of 13.29 μg/mL. Antibacterial agent 256 ameliorates the MRSA skin infection in mouse model .

Cat. No.	Product Name

HY-L147

Protease Inhibitor Library

678 compounds

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. Proteases play important roles in regulating multiple biological processes in all living organisms, such as regulating the fate, localization, and activity of many proteins, modulating protein-protein interactions, creating new bioactive molecules, contributing to the processing of cellular information, and generating, transducing, and amplifying molecular signals.

Proteases are important targets in drug discovery. Some protease inhibitors are often used as anti-virus drugs and anti-cancer drugs. MCE offers a unique collection of 678 protease inhibitors. MCE Protease Inhibitor Library is critical for drug discovery and development.

Cat. No.	Product Name	Type