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human cytomegalovirus (HCMV)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CMV (10) CDK (2) Fluorescent Dye (1) Histone Demethylase (1) HIV (2) HSV (3) PKC (1)
By Research Areas:	Cancer (2) Infection (12)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Isotope-Labeled Compounds

Targets Recommended: CMV

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99621

Fiztasovimab NPC-21; EV2038	CMV	Infection
Fiztasovimab (NPC-21; EV2038) is a fully human IgG1λ mAb against human cytomegalovirus (hCMV). Fiztasovimab acts neutralizing activity by binding to the antigenic domain 1 of glycoprotein B on hCMV envelope. Fiztasovimab inhibits cell-to-cell transmission of hCMV .

HY-12653

LDC4297 5 Publications Verification	CDK HIV HSV	Infection
LDC4297 is a selective inhibitor of CDK7 with an IC₅₀ value of 0.13 nM. LDC4297 inhibits human cytomegalovirus (HCMV) replication with an EC₅₀ value of 24.5 nM. LDC4297 shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC₅₀ value of 0.02-1.21 μM. LDC4297 can be used for the research of infection .

HY-P4777

Dabcyl-RGVVNASSRLA-Edans Dabcyl-CMV-Edans	Fluorescent Dye	Infection
Dabcyl-RGVVNASSRLA-Edans (Dabcyl-CMV-Edans) is a fluorogenic substrate for human cytomegalovirus (HCMV) protease .

HY-114005

SB-734117	CMV	Infection
SB-734117 is a human cytomegalovirus (HCMV) replication inhibitor that prevents CREB and histone H3 post-translational modifications .

HY-146271

pUL89 Endonuclease-IN-2	CMV	Infection
pUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC₅₀ of 3.0 μM. Antiviral activities .

HY-146270

pUL89 Endonuclease-IN-1	CMV	Infection
pUL89 Endonuclease-IN-1 (Compound 13d) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC₅₀ value of 0.88 μM and has antiviral activitiy .

HY-19296

BDCRB 2-Bromo-5,6-dichloro-1-β-D-ribofuranosyl benzimidazole	Others	Infection
BDCRB is a selective Human cytomegalovirus (HCMV) inhibitor through blocking the maturational cleavage of high-molecular-weight DNA. BDCRB shows a mean IC₅₀ of 0.03 μM for viral yield at 72 h postinfection .

HY-167900

CMV-423 RPR-111423	CMV	Infection
CMV-423 is an antiviral agent with potent in vitro activity against the beta-herpesvirus human cytomegalovirus (HCMV), human herpesvirus 6 (HHV-6) and 7 (HHV-7). CMV-423 can be utilized in antiviral research .

HY-103365

BX-513 hydrochloride VUF2274 hydrochloride	CMV	Infection
BX-513 hydrochloride (VUF 2274 hydrochloride)is a novel inverse agonists acting on human cytomegalovirus (HCMV)-encoded receptor US28 with the IC₅₀ of 4.9 μM. BX-513 hydrochloride can be used for study of viral infection .

HY-160917

BAY-43-9695	CMV	Infection
BAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC₅₀ of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC₅₀ of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261) .

HY-12653A

LDC4297 hydrochloride 5 Publications Verification	CDK HIV HSV	Infection
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC₅₀ value of 0.13 nM. LDC4297 hydrochloride inhibits human cytomegalovirus (HCMV) replication with an EC₅₀ value of 24.5 nM. LDC4297 hydrochloride shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC₅₀ values of 0.02-1.21 μM. LDC4297 hydrochloride can be used for the research of infection .

HY-12725

ML324 Maximum Cited Publications 6 Publications Verification	Histone Demethylase HSV CMV	Cancer
ML324 is a potent JMJD2 demethylase inhibitor with antiviral activity. ML324 also exhibits inhibition for the histone demethylase KDM4B, with an IC₅₀ of 4.9 μM. ML324 has potent anti-viral activity against both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection via inhibition viral IE gene expression .

HY-N1127S

Tricin-d6	CMV	Cancer
Tricin-d₆ is the deuterium labeled Tricin[1]. Tricin is a natural flavonoid present in large amounts in Triticum aestivum. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[2][3][4].

HY-108254

Bisindolylmaleimide IV Arcyriarubin A	PKC CMV	Infection
Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC₅₀s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC₅₀=3.1-11.8μM) . Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus *(HCMV)* replication in cell culture with an IC₅₀ of 0.2 μM .

Cat. No.	Product Name	Target	Research Area

HY-P4777

Dabcyl-RGVVNASSRLA-Edans Dabcyl-CMV-Edans	Fluorescent Dye	Infection
Dabcyl-RGVVNASSRLA-Edans (Dabcyl-CMV-Edans) is a fluorogenic substrate for human cytomegalovirus (HCMV) protease .

Cat. No.	Product Name	Target	Research Area

HY-P99621

Fiztasovimab NPC-21; EV2038	CMV	Infection
Fiztasovimab (NPC-21; EV2038) is a fully human IgG1λ mAb against human cytomegalovirus (hCMV). Fiztasovimab acts neutralizing activity by binding to the antigenic domain 1 of glycoprotein B on hCMV envelope. Fiztasovimab inhibits cell-to-cell transmission of hCMV .

Species:	Virus (3)
Tag:	Tag Free (1) Fc (2)
Source:	HEK293 (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P75161

	HCMV Glycoprotein B/gB Protein (HEK293, Fc) human cytomegalovirus (HCMV) Glycoprotein B / gB Protein; Envelope glycoprotein B; UL55	Virus	HEK293
	The gB Protein is an envelope glycoprotein that plays a role in host cell entry, cell-to-cell viral transmission, and infected cell fusion.gB Protein interacts with heparin sulfate proteoglycan and forms an association with gH/gL heterodimer.HCMV Glycoprotein B/gB Protein (HEK293, Fc) is a recombinant Virus-derived HCMV Glycoprotein B/gB protein(with cleavage site mutated RTKR to TTQT), expressed by HEK293 , with C-hFc labeled tag.HCMV Glycoprotein B/gB Protein (HEK293, Fc), has molecular weight of 160-170 kDa.

HY-P74875

	HCMV Glycoprotein B/gB Protein (HEK293) human cytomegalovirus (HCMV) Glycoprotein B / gB Protein	Virus	HEK293
	The gB Protein is an envelope glycoprotein that plays a role in host cell entry, cell-to-cell viral transmission, and infected cell fusion. gB Protein interacts with heparin sulfate proteoglycan and forms an association with gH/gL heterodimer. HCMV Glycoprotein B/gB Protein (HEK293) is a recombinant Virus-derived HCMV Glycoprotein B/gB protein(with cleavage site mutated RTKR to TTQT), expressed by HEK293 , with tag free. HCMV Glycoprotein B/gB Protein (HEK293), has molecular weight of 130-140 kDa.

HY-P76980

	HCMV Glycoprotein B/gB Protein (676a.a, HEK293, Fc) human cytomegalovirus (HCMV) Glycoprotein B / gB Protein (ECD, Fc)	Virus	HEK293
	The gB Protein is an envelope glycoprotein that plays a role in host cell entry, cell-to-cell viral transmission, and infected cell fusion. gB Protein interacts with heparin sulfate proteoglycan and forms an association with gH/gL heterodimer. HCMV Glycoprotein B/gB Protein (676a.a, HEK293, Fc) is the recombinant Virus-derived HCMV Glycoprotein B/gB protein, expressed by HEK293 , with C-hFc labeled tag. The total length of HCMV Glycoprotein B/gB Protein (676a.a, HEK293, Fc) is 676 a.a., with molecular weight of 135-145 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-N1127S

Tricin-d6
Tricin-d₆ is the deuterium labeled Tricin[1]. Tricin is a natural flavonoid present in large amounts in Triticum aestivum. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7[2][3][4].

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