2. Anti-infection
  3. CMV
  4. pUL89 Endonuclease-IN-1

pUL89 Endonuclease-IN-1 (Compound 13d) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 value of 0.88 μM and has antiviral activitiy.

For research use only. We do not sell to patients.

pUL89 Endonuclease-IN-1 Chemical Structure

pUL89 Endonuclease-IN-1 Chemical Structure

CAS No. : 391680-92-5

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pUL89 Endonuclease-IN-1 Related Antibodies

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Description

pUL89 Endonuclease-IN-1 (Compound 13d) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 value of 0.88 μM and has antiviral activitiy[1].

IC50 & Target

IC50:0.88μM (pUL89-C)
In Vitro

pUL89 Endonuclease-IN-1 (compound 13d) is strongly inhibited pUL89-C with the values of IC500.88μM. pUL89 Endonuclease-IN-1 reveals excellent aqueous solubility, plasma stability, and metabolic stability in vitro ADME. pUL89 Endonuclease-IN-1 displays moderately permeability in the PAMPA[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

pUL89 Endonuclease-IN-1 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: HFF cells
Concentration: 5 μM
Incubation Time: 168 h
Result: Showed significant inhibition for HCMV at 5 μM.
Molecular Weight

252.25

Formula

C10H8N2O4S
CAS No.
SMILES

COC(C1=C(C(O)=NC(C2=CC=CS2)=N1)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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pUL89 Endonuclease-IN-1 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

pUL89 Endonuclease-IN-1391680-92-5CMVCytomegalovirushuman cytomegalovirusHCMVpUL89 endonucleaseAntiviral activitiesInhibitorinhibitorinhibit

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