Search Result
Results for "
triterpenoid compound
" in MedChemExpress (MCE) Product Catalog:
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N4125
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3-O-Acetyldehydroeburicoic acid
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Others
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Inflammation/Immunology
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Dehydroeburicoic acid monoacetate (Compound 18) is a lanostane triterpenoid isolated from Wolfiporia cocos .
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- HY-N13161
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Others
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Others
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28-Hydroxy-12-oleanen-3-one is a triterpenoid compound that can be isolated from the fruit of the Dipteronia sinensis .
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- HY-N2895
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Arjuntriterpenic acid
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Others
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Others
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Arjunic acid (Arjuntriterpenic acid) (compound 13) is a triterpenoid compound isolated from Sanguisorba officinalis L .
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- HY-N3666
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3β-Cycloeucalenol
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Others
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Others
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Cycloeucalenol is a triterpenoid compound derived from Eucalyptus microcorys .
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- HY-N12160
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Others
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Others
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Erythrodiol diacetate (Compound 4) is a triterpenoid compound derived from Erythrina eriotriocha stem bark .
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- HY-107235
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Clematoside S; Prosapogenin CP6
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Others
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Others
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Saponin CP6 is a triterpenoid compound from the roots of Clematis grata .
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- HY-N8602
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Others
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Others
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Ganoderenic acid F (compound 17) is a triterpenoid that can be found in ganoderma lucidum .
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- HY-N12159
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Others
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Others
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Uvaol diacetate (Compound 5) is a type of triterpenoids derived from Nerium oleunder L. leaves .
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- HY-N12587
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- HY-N13106
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Others
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Others
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Camelliagenin A 22-angelate (compound 5) is a triterpenoid isolated from the bark of birch .
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- HY-N8915
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Others
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Others
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Deoxyflindissone (Compound 13) is a triterpenoid
compound. Deoxyflindissone is isolated from natural Cornus walteri
.Deoxyflindissone has significant cytotoxic activity
.
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- HY-N2965
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- HY-N1822
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Others
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Others
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3-epi-Cabraleahydroxylactone (compound 3) is a triterpenoid that can be found in Aglaia angustifolia Miq .
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- HY-N3227
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Others
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Cancer
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Myricadiol, a pentacyclic triterpenoid compound, is a potential lead compound for anticancer agent. Myricadiol can be isolated from Scaevola spinescens R. Br. (Goodeniaceae) .
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- HY-126607
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Others
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Others
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Sericic acid (compound 7) is a triterpenoid obtained from the methanol extract of blackberry (Rubus allegheniensis Port.) fruit .
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- HY-N0140
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Prunol; Urson; Malol
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Autophagy
Endogenous Metabolite
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Cancer
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Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
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- HY-N4064
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Others
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Others
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Hederagenic acid (compound 2) is a kind of triterpenoid saponin. Hederagenic acid can be isolated from the roots of Kalopanax septemlobus (Thunb.) Koidz .
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- HY-N9319
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Decaisoside E
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Others
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Others
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Fulvotomentoside A (Decaisoside E) is a triterpenoid saponin compound isolated from the flowers of Lonicera fulvotomentosa Hsu et S.C. Cheng .
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- HY-120149
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Others
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Cancer
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Inotodiol (compound 3) is a lanostane-type triterpenoid compound isolated from the sclerotia of Inonotus obliquus. Inotodiol exhibits the potent anti-tumor promoting activity in the in vivo carcinogenesis test .
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- HY-N3303
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Others
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Others
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Meliasenin B (compound 2) is an apotirucallane-type triterpenoid. Meliasenin B is a nature product that could be isolated from the fruits of Melia azedarach .
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- HY-N0892
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- HY-N3500
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- HY-N7640
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Others
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Inflammation/Immunology
Cancer
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Desoxylimonin is an orally active triterpenoid compound found from grapefruit seed. Desoxylimonin shows anti-proliferative activities to breast cancer cells. Desoxylimonin derivatives shows better anticancer, analgesic and anti-inflammatory activity than the lead compound .
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- HY-N10071
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Others
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Cancer
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Poricoic acid G is a triterpenoid that can be isolated from Poria cocos. Poricoic acid G has a significant cytotoxic effect on leukemia cells and is a potential potent anti-leukemic compound in humans .
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- HY-B2114
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Escin
2 Publications Verification
|
Apoptosis
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Metabolic Disease
Inflammation/Immunology
Cancer
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Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
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- HY-N0332
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- HY-N8152
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Reactive Oxygen Species
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Inflammation/Immunology
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Randialic acid B, a triterpenoid compound, is a formyl peptide receptor 1 (FPR1) antagonist. Randialic acid B blocks FPR1 in human neutrophils and attenuates psoriasis-like inflammation in vivo .
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- HY-122949
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DGK
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Metabolic Disease
|
Momordicine I, a triterpenoid compound extracted from momordica charantia L. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ .
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- HY-N8676
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Others
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Cancer
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Antiproliferative agent-29 (Compound 16) is a triterpenoid isolated from the seeds of Peganum harmala L. Antiproliferative agent-29 has antiproliferative activity and has potential for cancer research .
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- HY-N8677
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Others
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Cancer
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Antiproliferative agent-28 (Compound 14) is a triterpenoid isolated from the seeds of Peganum harmala L. Antiproliferative agent-28 has antiproliferative activity and has potential for cancer research .
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- HY-13324
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RTA 402; NSC 713200; CDDO Methyl ester
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Keap1-Nrf2
Autophagy
Apoptosis
Ferroptosis
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Cancer
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Bardoxolone methyl (NSC 713200; RTA 402; CDDO Methyl ester) is a synthetic triterpenoid compound with potential antineoplastic and anti-inflammatory activities, acting as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway.
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- HY-N9345
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Others
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Others
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(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton .
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- HY-N0140R
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Autophagy
Endogenous Metabolite
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Cancer
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Ursolic acid (Standard) is the analytical standard of Ursolic acid. This product is intended for research and analytical applications. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.
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- HY-N1178
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Interleukin Related
LXR
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Inflammation/Immunology
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Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. Taraxasterol may be used in research on immune-inflammatory diseases .
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- HY-N9304
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19a-Hydroxyferna-7,9(11)-diene
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Others
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Others
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Fern-7-en-19α-ol (9a-Hydroxyferna-7,9(11)-diene) is a triterpenoid compound isolated from Adiantum caudatum .
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- HY-N1508
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Others
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Inflammation/Immunology
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Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .
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- HY-N0587
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- HY-N3188
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Akt
NF-κB
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Infection
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Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways .
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- HY-N13115A
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(E)-21-Angeloyl-protoaescigenin
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Others
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Cancer
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Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively .
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- HY-N13115
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(Z)-Protoescigenin 21-tiglate
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Others
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Cancer
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21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively .
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- HY-N0892R
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- HY-N3242
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-
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- HY-N12846
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Others
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Metabolic Disease
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Neokadsuranic acid A is a cholesterol biosynthesis inhibitor that reduces the activity of cholesterol. Neokadsuranic acid A is a triterpenoid compound that can be isolated from Kadsura heteroclita, a plant of the Schisandraceae family. Neokadsuranic acid A can be used to study the cholesterol biosynthesis pathway and its role in traditional medicine .
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- HY-N4063
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FXR
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Inflammation/Immunology
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Hedragonic acid is an oleane-type triterpenoid compound, which can be isolated from the stems and roots of the southern snake vine. Hedragonic acid is a ligand and agonist for FXR. Hedragonic acid protected mice from liver damage caused by acetaminophen overdose and reduced liver inflammation .
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- HY-126462
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Others
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Infection
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Lantic acid is a triterpenoid compound possessing antimicrobial activity. Lantic acid exhibits inhibitory effects on a broad range of both Gram-positive and Gram-negative bacteria, with particular potency against Escherichia coli and Bacillus subtilis. Lantic acid is utilized in the research and development of antimicrobial agents .
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- HY-126662
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Bacterial
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Infection
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Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
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- HY-N0611
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α-Boswellic acid
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Others
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Neurological Disease
Inflammation/Immunology
Cancer
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alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .
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- HY-N12137
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Others
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Cancer
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Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents .
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- HY-N8987
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Others
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Others
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(3β,7β)-3,7,23,24-Tetrahydroxycucurbita-5,25-dien-19-al (compound 3) is a cucurbitane-type triterpenoid isolated from the vines and leaves of Momordica charantia .
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- HY-N0332R
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Reactive Oxygen Species
Apoptosis
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Inflammation/Immunology
Cancer
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Ziyuglycoside II (Standard) is the analytical standard of Ziyuglycoside II. This product is intended for research and analytical applications. Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .
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- HY-149586
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Reactive Oxygen Species
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Others
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ROS-IN-2 (compound 85) is a seco-lupane triterpenoid derivative. ROS-IN-2 blocks ROS production and protects mitochondria from damage by inhibiting excessive production of oxidative stressors. ROS-IN-2 can be used for myocardial ischemia/reperfusion (MI/R) injury research .
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- HY-N1508R
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Others
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Inflammation/Immunology
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Ecliptasaponin A (Standard) is the analytical standard of Ecliptasaponin A. This product is intended for research and analytical applications. Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .
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- HY-N0587R
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- HY-N9295
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Others
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Metabolic Disease
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3, 4-seco-4 (23),20(29) -Lupadiene-3,28-dioic acid
(Compound 5) is a triterpenoid compound. 3, 4-seco-4 (23),20(29)
-Lupadiene-3,28-dioic acid has a strong inhibitory effect on the production of
superoxide anions, and the inhibitory rate is 86.9±2.8% at 1 μM
.
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- HY-N8423
-
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ERK
GSK-3
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Neurological Disease
Metabolic Disease
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α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can be used in the study of metabolic syndrome induced by high fructose diet and cognitive dysfunction caused by low cholinergic neurotransmission .
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- HY-N12161
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Others
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Metabolic Disease
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3-Acetyl-11-keto-ursolic acid (Compound 18) is a triterpenoid compound derived from Eriobotrya japonicaleaves. 3-Acetyl-11-keto-ursolic acid has 11B-hydroxysteroid dehydrogenase 1 (11b-HSD1) inhibitory activity. 3-Acetyl-11-keto-ursolic acid can be used for anti-diabetes research .
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- HY-N10760
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Others
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Metabolic Disease
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2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid (compound 3), a triterpenoid, significantly decreases the level of fibronectin in High-Glucose and TGF-b1 induced HK-2 cells with 27.66 % inhibition rate at 10 μM .
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- HY-N13164
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PI3K
Akt
Apoptosis
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Cancer
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Polygalacin D3 is a triterpenoid saponin compound that can be extracted from the roots of the balloon flower. Polygalacin D3 can inhibit the proliferation of non-small cell lung cancer (NSCLC) cell lines by blocking the PI3K/Akt pathway, and it induces cell cycle arrest and cell apoptosis .
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- HY-N13162
-
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Others
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Cancer
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Hemsleyadin D is a triterpenoid compound derived from Hemsleya penxianensis with antitumor activity. Its IC50 values against K562, MGC-803, U118, HepG2, A549, and MCF-7 cells are 93.9, 47.1, 25.9, 56.1, 66.3, and 67.6 μM, respectively .
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- HY-N11020
-
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EBV
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Infection
Inflammation/Immunology
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Cabenoside D (compound 8) is a triterpenoid glycoside, which can be isolated from the methanol extract of lichen root. Cabenoside D shows anti-inflammatory activity and inhibits inflammation induced by 12-O-tetracylacyl hormone-13-acetate (TPA) in mice. Cabenoside D also inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation .
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- HY-N0611R
-
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Others
|
Neurological Disease
Inflammation/Immunology
Cancer
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alpha-Boswellic acid (Standard) is the analytical standard of alpha-Boswellic acid. This product is intended for research and analytical applications. alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .
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- HY-112671
-
RTA dh404
|
Keap1-Nrf2
NF-κB
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Inflammation/Immunology
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CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB . CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats .
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- HY-126741
-
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Apoptosis
Parasite
NF-κB
Bcl-2 Family
Caspase
|
Infection
Inflammation/Immunology
Cancer
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Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation). Additionally, Azadirachtin exerts its anti-inflammatory effects by inhibiting NF-кB signaling pathway activation, and it exhibits insecticidal activity by inducing apoptosis in insect cells .
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- HY-N9284
-
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Others
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Cancer
|
5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol is a triterpenoid compound derived from Momordica charantia with antitumor activity, exhibiting an IC50 of 32.52 μM against U937 cells. 5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol shows promise for research in the field of cancer .
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- HY-N13176
-
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Autophagy
Apoptosis
PI3K
Akt
mTOR
FAK
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Cancer
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Stellettin B is a triterpenoid compound that can be isolated from the marine sponge Jaspis stellifera. Stellettin B induces G1 phase arrest, apoptosis, and autophagy in human non-small cell lung cancer A549 cells by blocking the PI3K/Akt/mTOR pathway. Stellettin B can reduce the migration and invasion of liver cancer cells by decreasing the activation of the MAPK and FAK/PI3K/AKT/mTOR signaling pathways. Stellettin B can be used in the study of various tumors .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N4125
-
-
-
- HY-N13161
-
-
-
- HY-N2895
-
-
-
- HY-N3666
-
-
-
- HY-N12160
-
-
-
- HY-107235
-
-
-
- HY-N8602
-
-
-
- HY-N12159
-
-
-
- HY-N12587
-
-
-
- HY-N13106
-
-
-
- HY-N8915
-
-
-
- HY-N2965
-
-
-
- HY-N1822
-
-
-
- HY-N3227
-
-
-
- HY-126607
-
-
-
- HY-N0140
-
-
-
- HY-N4064
-
-
-
- HY-N9319
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-
-
- HY-120149
-
-
-
- HY-N3303
-
-
-
- HY-N0892
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-
-
- HY-N3500
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-
-
- HY-N7640
-
-
-
- HY-N10071
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-
-
- HY-B2114
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-
-
- HY-N0332
-
-
-
- HY-N8152
-
-
-
- HY-122949
-
-
-
- HY-N8676
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-
-
- HY-N8677
-
-
-
- HY-N9345
-
-
-
- HY-N0140R
-
-
-
- HY-N1178
-
-
-
- HY-N1508
-
-
-
- HY-N0587
-
-
-
- HY-N3188
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-
-
- HY-N13115A
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(E)-21-Angeloyl-protoaescigenin
|
Aesculus chinensis Bunge
Triterpenes
Structural Classification
Terpenoids
Hippocastanaceae
Source classification
Plants
|
Others
|
Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively .
|
-
-
- HY-N13115
-
(Z)-Protoescigenin 21-tiglate
|
Aesculus chinensis Bunge
Triterpenes
Structural Classification
Terpenoids
Hippocastanaceae
Source classification
Plants
|
Others
|
21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively .
|
-
-
- HY-N0892R
-
-
-
- HY-N3242
-
-
-
- HY-N12846
-
-
-
- HY-N4063
-
-
-
- HY-126462
-
-
-
- HY-126662
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-
-
- HY-N0611
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-
-
- HY-N12137
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-
-
- HY-N8987
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-
-
- HY-N0332R
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-
-
- HY-N1508R
-
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Triterpenes
Structural Classification
other families
Terpenoids
Source classification
Plants
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Others
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Ecliptasaponin A (Standard) is the analytical standard of Ecliptasaponin A. This product is intended for research and analytical applications. Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .
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-
- HY-N0587R
-
-
- HY-N9295
-
-
- HY-N8423
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-
- HY-N12161
-
-
- HY-N10760
-
-
- HY-N13164
-
-
- HY-N13162
-
|
Triterpenes
Structural Classification
Terpenoids
Source classification
Cucurbitaceae
Plants
Hemsleya pengxianensis W. J. Chang
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Others
|
Hemsleyadin D is a triterpenoid compound derived from Hemsleya penxianensis with antitumor activity. Its IC50 values against K562, MGC-803, U118, HepG2, A549, and MCF-7 cells are 93.9, 47.1, 25.9, 56.1, 66.3, and 67.6 μM, respectively .
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-
- HY-N11020
-
-
- HY-N0611R
-
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Triterpenes
Structural Classification
Terpenoids
Source classification
Boswellia serrata
Plants
Burseraceae
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Others
|
alpha-Boswellic acid (Standard) is the analytical standard of alpha-Boswellic acid. This product is intended for research and analytical applications. alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .
|
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- HY-126741
-
-
- HY-N9284
-
-
- HY-N13176
-
-
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- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: