1. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  2. ADC Cytotoxin DNA Alkylator/Crosslinker
  3. Seco-Duocarmycin TM

Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC)[1].

For research use only. We do not sell to patients.

Seco-Duocarmycin TM Chemical Structure

Seco-Duocarmycin TM Chemical Structure

CAS No. : 236102-87-7

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Description

Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC)[1].

IC50 & Target

Duocarmycins

 

Molecular Weight

448.47

Formula

C25H24N2O6

CAS No.
SMILES

OC[C@H]1C2=C(C=CC=C3)C3=C(O)C=C2N(C(C4=CC(C=C(OC)C(OC)=C5OC)=C5N4)=O)C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Seco-Duocarmycin TM
Cat. No.:
HY-130083
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