2. Immunology/Inflammation MAPK/ERK Pathway Metabolic Enzyme/Protease Autophagy Anti-infection
  3. Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Autophagy Bacterial Fungal
  4. Skatole-d3

Skatole-d3  (Synonyms: 3-Methylindole-d3; 3-Methyl-1H-indole-d3)

Cat. No.: HY-W007355S Purity: ≥98.0%
SDS COA Handling Instructions

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Skatole-d3 is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38[1].

For research use only. We do not sell to patients.

Skatole-d<sub>3</sub> Chemical Structure

Skatole-d3 Chemical Structure

CAS No. : 111399-60-1

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1 mg USD 150 In-stock
5 mg USD 330 In-stock
10 mg USD 540 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Skatole-d3:

Skatole-d3 Related Antibodies

Top Publications Citing Use of Products

View All p38 MAPK Isoform Specific Products:

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

  • Biological Activity

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Description

Skatole-d3 is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Skatole-d3 Related Antibodies
Molecular Weight

134.19

Formula

C9H6D3N
CAS No.
Unlabeled CAS

83-34-1
Appearance

Solid

Color

White to off-white

SMILES

[2H]C(C1=CNC2=C1C=CC=C2)([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (745.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 100 mg/mL (745.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.4521 mL 37.2606 mL 74.5212 mL
5 mM 1.4904 mL 7.4521 mL 14.9042 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

SDS (251 KB)

COA (255 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 7.4521 mL 37.2606 mL 74.5212 mL 186.3030 mL
5 mM 1.4904 mL 7.4521 mL 14.9042 mL 37.2606 mL
10 mM 0.7452 mL 3.7261 mL 7.4521 mL 18.6303 mL
15 mM 0.4968 mL 2.4840 mL 4.9681 mL 12.4202 mL
20 mM 0.3726 mL 1.8630 mL 3.7261 mL 9.3151 mL
25 mM 0.2981 mL 1.4904 mL 2.9808 mL 7.4521 mL
30 mM 0.2484 mL 1.2420 mL 2.4840 mL 6.2101 mL
40 mM 0.1863 mL 0.9315 mL 1.8630 mL 4.6576 mL
50 mM 0.1490 mL 0.7452 mL 1.4904 mL 3.7261 mL
60 mM 0.1242 mL 0.6210 mL 1.2420 mL 3.1050 mL
80 mM 0.0932 mL 0.4658 mL 0.9315 mL 2.3288 mL
100 mM 0.0745 mL 0.3726 mL 0.7452 mL 1.8630 mL
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Skatole-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Skatole-d3111399-60-13-Methylindole-d33-Methyl-1H-indole-d3Aryl Hydrocarbon Receptorp38 MAPKEndogenous MetaboliteAutophagyBacterialFungalAhRInhibitorinhibitorinhibit

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