1. Others GPCR/G Protein Neuronal Signaling
  2. Isotope-Labeled Compounds 5-HT Receptor Serotonin Transporter
  3. Vortioxetine-d8

Vortioxetine-d8 (Lu AA 21004-d8) is a deuterated version of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM).

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Vortioxetine-d<sub>8</sub> Chemical Structure

Vortioxetine-d8 Chemical Structure

CAS No. : 2140316-62-5

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Description

Vortioxetine-d8 (Lu AA 21004-d8) is a deuterated version of Vortioxetine. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM)[1].

Molecular Weight

306.49

Formula

C18H14D8N2S

CAS No.
Unlabeled CAS

508233-74-7

SMILES

CC1=CC=C(SC2=CC=CC=C2N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])C(C)=C1

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Vortioxetine-d8
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HY-15414S
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