2. Metabolic Enzyme/Protease
  3. Adenosine Deaminase
  4. 1-Deazaadenosine

1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders.

For research use only. We do not sell to patients.

1-Deazaadenosine Chemical Structure

1-Deazaadenosine Chemical Structure

CAS No. : 14432-09-8

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Based on 1 publication(s) in Google Scholar

1-Deazaadenosine Related Antibodies

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Description

1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders[1][2].

In Vitro

1-Deazaadenosine shows good activity in vitro as inhibitor of HeLa, KB, P388, and L1210 leukemia cell line growth, with ID50 values ranging from 0.34 μM (KB) to 1.8 μM (P388)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1-Deazaadenosine Related Antibodies
Molecular Weight

266.25

Formula

C11H14N4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H](CO)O3)O)O)C=N2)=NC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

COA (250 KB)

Handling Instructions (2659 KB)
References
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1-Deazaadenosine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Deazaadenosine14432-09-8Adenosine DeaminaseleukemiachemotherapycancerHeLaKBP388L1210Inhibitorinhibitorinhibit

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