2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. CDKL

CDKL

Cyclin-dependent kinase-like family

Cyclin-dependent kinase-like (CDKL) family proteins are serine/threonine protein kinases. Its name is due to the sequence similarity with CDK and it consists of 5 members (CDKL1-5). Their function in protein phosphorylation underpins their important role in cellular activities, including cell cycle, apoptosis, autophagy and microtubule dynamics.

CDKL Related Products (1):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-172198
    GSK3-IN-10
    		Inhibitor
    GSK3-IN-10 (Compound 4) is a multi-target inhibitor, that mainly targets GSK3α and GSK3β with IC50 of 1.0 nM and 2.0 nM. GSK3-IN-10 inhibits the activation of β-catenin, promotes the neuronal survival, and exhibits a protective effect against endoplasmic reticulum stress.
    GSK3-IN-10