2. Metabolic Enzyme/Protease
  3. 11β-HSD
  4. 11β-HSD1-IN-9

11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment.

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11β-HSD1-IN-9 Chemical Structure

11β-HSD1-IN-9 Chemical Structure

CAS No. : 88283-34-5

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11β-HSD1-IN-9 Related Antibodies

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Description

11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].

Molecular Weight

266.22

Formula

C13H9F3N2O
CAS No.
SMILES

C1=C(C=CC(=C1)C(F)(F)F)C(=O)CC2=CN=CC=N2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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11β-HSD1-IN-9 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11β-HSD1-IN-988283-34-511β-HSD11beta-HSD11β-hydroxysteroid dehydrogenases11 beta-hydroxysteroid dehydrogenaseglucocorticoidsobesityhyperglycemiacognitive impairmentInhibitorinhibitorinhibit

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