1. GPCR/G Protein
  2. Leukotriene Receptor
  3. 12-epi-LTB4

12-epi-LTB4 is an agonist for BLT1 and BLT2. 12-epi LTB4 exhibits a partial agonistic activity against mBLT1 and mBLT2, and induces phosphorylation of extracellular signal-regulated kinase in primary mouse keratinocytes.

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12-epi-LTB4 Chemical Structure

12-epi-LTB4 Chemical Structure

CAS No. : 83709-73-3

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Description

12-epi-LTB4 is an agonist for BLT1 and BLT2. 12-epi LTB4 exhibits a partial agonistic activity against mBLT1 and mBLT2, and induces phosphorylation of extracellular signal-regulated kinase in primary mouse keratinocytes[1][2].

In Vivo

BLT1 and BLT2[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

336.47

Formula

C20H32O4

CAS No.
SMILES

O[C@@H](CCCC(O)=O)/C=C\C=C\C=C\[C@@H](O)C/C=C\CCCCC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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12-epi-LTB4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
12-epi-LTB4
Cat. No.:
HY-137350
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