13,14-Dihydro-15-keto Prostaglandin F2α-d₄  (Synonyms: 13,14-Dihydro-15-keto-PGF2α-d₄)

13,14-Dihydro-15-keto Prostaglandin F2α-d4 (13,14-Dihydro-15-keto-PGF2α-d4) is a deuterated labeled 13,14-Dihydro-15-keto Prostaglandin F2α (HY-113208). 13,14-Dihydro-15-keto Prostaglandin F2α-d4 is an endogenous metabolite present in Blood that can be used for the research of Pregnancy^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

358.51

C₂₀H₃₀D₄O₅

42932-59-2

27376-76-7

OC(CC([2H])([2H])C([2H])([2H])/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)CCC(CCCCC)=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. E W HORTON, et al. A COMPARISON OF THE BIOLOGICAL ACTIVITIES OF FOUR PROSTAGLANDINS. Br J Pharmacol Chemother  [Content Brief]