1. Metabolic Enzyme/Protease
  2. Lipoxygenase
  3. 15(S)-HETRE

15(S)-HETRE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.

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15(S)-HETRE Chemical Structure

15(S)-HETRE Chemical Structure

CAS No. : 92693-02-2

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Description

15(S)-HETRE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.

Molecular Weight

322.48

Formula

C20H34O3

CAS No.
SMILES

CCCCC[C@H](/C=C/C=C\C/C=C\CCCCCCC(O)=O)O

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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15(S)-HETRE Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
15(S)-HETRE
Cat. No.:
HY-113776
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