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  4. 18-O-Demethylpederin

18-O-Demethylpederin is a pederin analogue. Pederin is a natural polyketide compound extracted from Paederus for the first time. It is a non-protein insect toxin with a broad spectrum of biological activities, including antibacterial, antiviral, and antitumor.

For research use only. We do not sell to patients.

18-O-Demethylpederin Chemical Structure

18-O-Demethylpederin Chemical Structure

CAS No. : 2120362-33-4

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Description

18-O-Demethylpederin is a pederin analogue. Pederin is a natural polyketide compound extracted from Paederus for the first time. It is a non-protein insect toxin with a broad spectrum of biological activities, including antibacterial, antiviral, and antitumor[1].

Cellular Effect
Cell Line Type Value Description References
A549 GI50
2 nM
Compound: 1
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
HT-29 GI50
2 nM
Compound: 1
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
MDA-MB-231 GI50
2 nM
Compound: 1
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
PSN1 GI50
2 nM
Compound: 1
Antiproliferative activity against human PSN1 cells assessed as growth inhibition after 72 hrs by SRB assay
Antiproliferative activity against human PSN1 cells assessed as growth inhibition after 72 hrs by SRB assay
[PMID: 28696720]
Molecular Weight

489.60

Formula

C24H43NO9

CAS No.
SMILES

O[C@@H]([C@@](CC([C@H]1C)=C)(O[C@@H]1C)OC)C(N[C@H]([C@@](C[C@H]2O)([H])O[C@@H](C(C)2C)C[C@H](OC)CO)OC)=O

Structure Classification
Initial Source

insects, lichen, and marine sponges

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
18-O-Demethylpederin
Cat. No.:
HY-N11667
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