1. Anti-infection
  2. Fungal
  3. 2,6-Dihydroxy-4-methoxyacetophenone

2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin, that can be isolated from the root tissue of Sanguisorba minor. 2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity. 2,6-Dihydroxy-4-methoxyacetophenone is a strong germination inhibitor on B. cinerea.

For research use only. We do not sell to patients.

2,6-Dihydroxy-4-methoxyacetophenone Chemical Structure

2,6-Dihydroxy-4-methoxyacetophenone Chemical Structure

CAS No. : 7507-89-3

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Description

2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin, that can be isolated from the root tissue of Sanguisorba minor. 2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity. 2,6-Dihydroxy-4-methoxyacetophenone is a strong germination inhibitor on B. cinerea[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
200 μM
Compound: 117, ZINC00900185
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter driven TK-luciferase reporter gene assay
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter driven TK-luciferase reporter gene assay
[PMID: 25581017]
In Vitro

2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity against two non-pathogenic fungi, Botrytis cinerea and Phomopsis perniciosa. The ED50s on spore germination were 45 and 410 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

182.17

Formula

C9H10O4

CAS No.
SMILES

CC(C1=C(O)C=C(OC)C=C1O)=O

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Purity & Documentation
References
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2,6-Dihydroxy-4-methoxyacetophenone Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2,6-Dihydroxy-4-methoxyacetophenone
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HY-N9695
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